| Literature DB >> 23223959 |
Claudio Parolo1, Mariana Medina-Sánchez, Alfredo de la Escosura-Muñiz, Arben Merkoçi.
Abstract
Lateral flow immunoassays (LFIA) are ideal biosensors to detect proteins, but their lack of sensitivity hinders their extensive use. We report a strategy that yields up to an 8-fold improvement in the sensitivity of a gold nanoparticles-based LFIA by changing the sizes of the pads. Theoretical flow simulations of the developed LFIA architectures are in accordance with the experimental results.Mesh:
Substances:
Year: 2013 PMID: 23223959 DOI: 10.1039/c2lc41144j
Source DB: PubMed Journal: Lab Chip ISSN: 1473-0189 Impact factor: 6.799