Literature DB >> 23223959

Simple paper architecture modifications lead to enhanced sensitivity in nanoparticle based lateral flow immunoassays.

Claudio Parolo1, Mariana Medina-Sánchez, Alfredo de la Escosura-Muñiz, Arben Merkoçi.   

Abstract

Lateral flow immunoassays (LFIA) are ideal biosensors to detect proteins, but their lack of sensitivity hinders their extensive use. We report a strategy that yields up to an 8-fold improvement in the sensitivity of a gold nanoparticles-based LFIA by changing the sizes of the pads. Theoretical flow simulations of the developed LFIA architectures are in accordance with the experimental results.

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Year:  2013        PMID: 23223959     DOI: 10.1039/c2lc41144j

Source DB:  PubMed          Journal:  Lab Chip        ISSN: 1473-0189            Impact factor:   6.799


  16 in total

1.  Increasing Binding Efficiency via Reporter Shape and Flux in a Viral Nanoparticle Lateral-Flow Assay.

Authors:  Jinsu Kim; Binh Vu; Katerina Kourentzi; Richard C Willson; Jacinta C Conrad
Journal:  ACS Appl Mater Interfaces       Date:  2017-02-15       Impact factor: 9.229

2.  A comparison of nanoparticle-antibody conjugation strategies in sandwich immunoassays.

Authors:  Justina O Tam; Helena de Puig; Chun-Wan Yen; Irene Bosch; Jose Gómez-Márquez; Charles Clavet; Kimberly Hamad-Schifferli; Lee Gehrke
Journal:  J Immunoassay Immunochem       Date:  2016-12-16

3.  Orientational binding modes of reporters in a viral-nanoparticle lateral flow assay.

Authors:  Jinsu Kim; Ryan Poling-Skutvik; João R C Trabuco; Katerina Kourentzi; Richard C Willson; Jacinta C Conrad
Journal:  Analyst       Date:  2016-12-19       Impact factor: 4.616

4.  Tapered lateral flow immunoassay based point-of-care diagnostic device for ultrasensitive colorimetric detection of dengue NS1.

Authors:  Sanjay Kumar; Pulak Bhushan; Vinay Krishna; Shantanu Bhattacharya
Journal:  Biomicrofluidics       Date:  2018-05-14       Impact factor: 2.800

5.  Magnetically-enabled biomarker extraction and delivery system: towards integrated ASSURED diagnostic tools.

Authors:  Westley S Bauer; Danielle W Kimmel; Nicholas M Adams; Lauren E Gibson; Thomas F Scherr; Kelly A Richardson; Joseph A Conrad; Hellen K Matakala; Frederick R Haselton; David W Wright
Journal:  Analyst       Date:  2017-05-02       Impact factor: 4.616

Review 6.  Challenges of the Nano-Bio Interface in Lateral Flow and Dipstick Immunoassays.

Authors:  Helena de Puig; Irene Bosch; Lee Gehrke; Kimberly Hamad-Schifferli
Journal:  Trends Biotechnol       Date:  2017-09-28       Impact factor: 19.536

7.  Disposable Autonomous Device for Swab-to-Result Diagnosis of Influenza.

Authors:  Shichu Huang; Koji Abe; Steven Bennett; Tinny Liang; Paula D Ladd; Lindsay Yokobe; Caitlin E Anderson; Kamal Shah; Josh Bishop; Mike Purfield; Peter C Kauffman; Sai Paul; AnneMarie E Welch; Bonnie Strelitz; Kristin Follmer; Kelsey Pullar; Luis Sanchez-Erebia; Emily Gerth-Guyette; Gonzalo Domingo; Eileen Klein; Janet A Englund; Elain Fu; Paul Yager
Journal:  Anal Chem       Date:  2017-05-08       Impact factor: 6.986

Review 8.  Tutorial: design and fabrication of nanoparticle-based lateral-flow immunoassays.

Authors:  Claudio Parolo; Amadeo Sena-Torralba; José Francisco Bergua; Enric Calucho; Celia Fuentes-Chust; Liming Hu; Lourdes Rivas; Ruslan Álvarez-Diduk; Emily P Nguyen; Stefano Cinti; Daniel Quesada-González; Arben Merkoçi
Journal:  Nat Protoc       Date:  2020-10-23       Impact factor: 13.491

9.  Modification of a nitrocellulose membrane with nanofibers for sensitivity enhancement in lateral flow test strips.

Authors:  Xue Wang; Chao-Hua Xue; Dong Yang; Shun-Tian Jia; Ya-Ru Ding; Lei Lei; Ke-Yi Gao; Tong-Tong Jia
Journal:  RSC Adv       Date:  2021-08-02       Impact factor: 4.036

10.  Gold-nanoparticle-decorated silica nanorods for sensitive visual detection of proteins.

Authors:  Hui Xu; Jiao Chen; Joseph Birrenkott; Julia Xiaojun Zhao; Sunitha Takalkar; Kwaku Baryeh; Guodong Liu
Journal:  Anal Chem       Date:  2014-07-24       Impact factor: 6.986

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