Literature DB >> 23221364

Deliverable navigation for multicriteria step and shoot IMRT treatment planning.

David Craft1, Christian Richter.   

Abstract

We consider Pareto surface based multi-criteria optimization for step and shoot IMRT planning. By analyzing two navigation algorithms, we show both theoretically and in practice that the number of plans needed to form convex combinations of plans during navigation can be kept small (much less than the theoretical maximum number needed in general, which is equal to the number of objectives for on-surface Pareto navigation). Therefore a workable approach for directly deliverable navigation in this setting is to segment the underlying Pareto surface plans and then enforce the mild restriction that only a small number of these plans are active at any time during plan navigation, thus limiting the total number of segments used in the final plan.

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Year:  2012        PMID: 23221364      PMCID: PMC3540824          DOI: 10.1088/0031-9155/58/1/87

Source DB:  PubMed          Journal:  Phys Med Biol        ISSN: 0031-9155            Impact factor:   3.609


  13 in total

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