Literature DB >> 23211454

Possible efficacy of Lavender and Tea tree oils in the treatment of young women affected by mild idiopathic hirsutism.

G Tirabassi1, L Giovannini, F Paggi, G Panin, F Panin, R Papa, M Boscaro, G Balercia.   

Abstract

BACKGROUND: Hirsutism is defined as the presence of excessive terminal hair in androgen-dependent areas of a woman's body. Regarding this it has been suggested that Lavender and Tea tree oils may have antiandrogenic activities. AIM: To evaluate therapy based on Lavender and Tea tree oils in women suffering from mild idiopathic hirsutism (IH). SUBJECTS AND METHODS: A prospective, open-label, placebo- controlled, randomized study was performed: women affected by mild IH were randomly assigned to receive oil spray containing Lavender and Tea tree oils (group T) (no. = 12) or placebo (group P) (no. = 12) twice a day for 3 months in areas affected by hirsutism. Evaluation of hirsutism was carried out at baseline and after 3 months by Ferriman-Gallwey score and by measuring hair diameter taken from some body areas. A hematological and hormonal evaluation was carried out at baseline and after 3 months.
RESULTS: No significant variations were found in any of the hormones studied in groups T and P between baseline and after 3 months. A statistically significant decrease of hirsutism total score and of hair diameter was found in group T, while no statistically significant difference in these two parameters was observed in group P; in group T percentual reduction of hair diameter was significantly greater than in group P.
CONCLUSIONS: Lavender and Tea tree oils applied locally on skin could be effective in reducing mild IH; this treatment could represent a safe, economic and practical instrument in the cure of this disease.

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Year:  2012        PMID: 23211454     DOI: 10.3275/8766

Source DB:  PubMed          Journal:  J Endocrinol Invest        ISSN: 0391-4097            Impact factor:   4.256


  25 in total

1.  Mild adrenal and ovarian steroidogenic abnormalities in hirsute women without hyperandrogenemia: does idiopathic hirsutism exist?

Authors:  H F Escobar-Morreale; J Serrano-Gotarredona; R García-Robles; J Sancho; C Varela
Journal:  Metabolism       Date:  1997-08       Impact factor: 8.694

Review 2.  Epidemiology, diagnosis and management of hirsutism: a consensus statement by the Androgen Excess and Polycystic Ovary Syndrome Society.

Authors:  H F Escobar-Morreale; E Carmina; D Dewailly; A Gambineri; F Kelestimur; P Moghetti; M Pugeat; J Qiao; C N Wijeyaratne; S F Witchel; R J Norman
Journal:  Hum Reprod Update       Date:  2011-11-06       Impact factor: 15.610

3.  The metabolism of testosterone by human skin in disorders of hair growth.

Authors:  J S Jenkins; S Ash
Journal:  J Endocrinol       Date:  1973-11       Impact factor: 4.286

4.  Prepubertal gynecomastia linked to lavender and tea tree oils.

Authors:  Derek V Henley; Natasha Lipson; Kenneth S Korach; Clifford A Bloch
Journal:  N Engl J Med       Date:  2007-02-01       Impact factor: 91.245

5.  Antiparasitic activity of two Lavandula essential oils against Giardia duodenalis, Trichomonas vaginalis and Hexamita inflata.

Authors:  Therese Moon; Jenny M Wilkinson; Heather M A Cavanagh
Journal:  Parasitol Res       Date:  2006-06-02       Impact factor: 2.289

6.  Update on the management of hirsutism.

Authors:  Shannon Harrison; Najwa Somani; Wilma F Bergfeld
Journal:  Cleve Clin J Med       Date:  2010-06       Impact factor: 2.321

7.  Pharmacological profile of essential oils derived from Lavandula angustifolia and Melissa officinalis with anti-agitation properties: focus on ligand-gated channels.

Authors:  Liping Huang; Sawsan Abuhamdah; Melanie-Jayne R Howes; Christine L Dixon; Mark S J Elliot; Clive Ballard; Clive Holmes; Alistair Burns; Elaine K Perry; Paul T Francis; George Lees; Paul L Chazot
Journal:  J Pharm Pharmacol       Date:  2008-11       Impact factor: 3.765

8.  Hirsutism: implications, etiology, and management.

Authors:  R Hatch; R L Rosenfield; M H Kim; D Tredway
Journal:  Am J Obstet Gynecol       Date:  1981-08-01       Impact factor: 8.661

9.  A prospective study of the prevalence of nonclassical congenital adrenal hyperplasia among women presenting with hyperandrogenic symptoms and signs.

Authors:  Héctor F Escobar-Morreale; Raul Sanchón; José L San Millán
Journal:  J Clin Endocrinol Metab       Date:  2007-11-13       Impact factor: 5.958

Review 10.  Evaluation and treatment of women with hirsutism.

Authors:  Melissa H Hunter; Peter J Carek
Journal:  Am Fam Physician       Date:  2003-06-15       Impact factor: 3.292

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