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Literature DB >> 2320579

Amino acid and cDNA sequences of a vascular endothelial cell mitogen that is homologous to platelet-derived growth factor.

G Conn¹, M L Bayne, D D Soderman, P W Kwok, K A Sullivan, T M Palisi, D A Hope, K A Thomas.

Abstract

Glioma-derived vascular endothelial cell growth factor (GD-VEGF) is a 46-kDa dimeric glycoprotein mitogen with apparently greater specificity for vascular endothelial cells than the well-characterized fibroblast growth factors. The GD-VEGF cDNA sequence encodes a 190-amino acid residue subunit that is converted, by removal of an amino-terminal hydrophobic secretory leader sequence, to the mature 164-residue subunit characterized by direct amino acid sequencing. The GD-VEGF homodimeric subunit is homologous to the platelet-derived growth factor A and B chains and its oncogene homologue v-sis.

Entities: Disease Gene Species

Mesh：

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Year: 1990 PMID： 2320579 PMCID： PMC53743 DOI： 10.1073/pnas.87.7.2628

Source DB: PubMed Journal: Proc Natl Acad Sci U S A ISSN： 0027-8424 Impact factor: 11.205

27 in total

1. Pure brain-derived acidic fibroblast growth factor is a potent angiogenic vascular endothelial cell mitogen with sequence homology to interleukin 1.

Authors: K A Thomas; M Rios-Candelore; G Giménez-Gallego; J DiSalvo; C Bennett; J Rodkey; S Fitzpatrick
Journal: Proc Natl Acad Sci U S A Date: 1985-10 Impact factor: 11.205

2. Purification of a glycoprotein vascular endothelial cell mitogen from a rat glioma-derived cell line.

Authors: G Conn; D D Soderman; M T Schaeffer; M Wile; V B Hatcher; K A Thomas
Journal: Proc Natl Acad Sci U S A Date: 1990-02 Impact factor: 11.205

3. Enzymatic amplification of beta-globin genomic sequences and restriction site analysis for diagnosis of sickle cell anemia.

Authors: R K Saiki; S Scharf; F Faloona; K B Mullis; G T Horn; H A Erlich; N Arnheim
Journal: Science Date: 1985-12-20 Impact factor: 47.728

4. Rapid production of full-length cDNAs from rare transcripts: amplification using a single gene-specific oligonucleotide primer.

Authors: M A Frohman; M K Dush; G R Martin
Journal: Proc Natl Acad Sci U S A Date: 1988-12 Impact factor: 11.205

5. A general method applicable to the search for similarities in the amino acid sequence of two proteins.

Authors: S B Needleman; C D Wunsch
Journal: J Mol Biol Date: 1970-03 Impact factor: 5.469

6. Structure and sequence of the human c-sis/platelet-derived growth factor 2 (SIS/PDGF2) transcriptional unit.

Authors: C D Rao; H Igarashi; I M Chiu; K C Robbins; S A Aaronson
Journal: Proc Natl Acad Sci U S A Date: 1986-04 Impact factor: 11.205

7. Identification of a signal for nuclear targeting in platelet-derived-growth-factor-related molecules.

Authors: B A Lee; D W Maher; M Hannink; D J Donoghue
Journal: Mol Cell Biol Date: 1987-10 Impact factor: 4.272

8. Point mutations define a sequence flanking the AUG initiator codon that modulates translation by eukaryotic ribosomes.

Authors: M Kozak
Journal: Cell Date: 1986-01-31 Impact factor: 41.582

9. Platelet-derived growth factor A chain: gene structure, chromosomal location, and basis for alternative mRNA splicing.

Authors: D T Bonthron; C C Morton; S H Orkin; T Collins
Journal: Proc Natl Acad Sci U S A Date: 1988-03 Impact factor: 11.205

10. DNA sequencing with chain-terminating inhibitors.

Authors: F Sanger; S Nicklen; A R Coulson
Journal: Proc Natl Acad Sci U S A Date: 1977-12 Impact factor: 11.205

66 in total

1. The role of the vascular phase in solid tumor growth: a historical review.

Authors: D Ribatti; A Vacca; F Dammacco
Journal: Neoplasia Date: 1999-10 Impact factor: 5.715

Review 2. Role of vascular permeability factor/vascular endothelial growth factor in eye disease.

Authors: R O Schlingemann; V W van Hinsbergh
Journal: Br J Ophthalmol Date: 1997-06 Impact factor: 4.638

3. The effects of growth factors on the day 13 chorioallantoic membrane (CAM): a study of VEGF165 and PDGF-BB.

Authors: J Wilting; B Christ; H A Weich
Journal: Anat Embryol (Berl) Date: 1992-08

4. Vascular endothelial growth factor-A signaling in bone marrow-derived endothelial progenitor cells exposed to hypoxic stress.

Authors: Brian R Hoffmann; Jordan R Wagner; Anthony R Prisco; Agnieszka Janiak; Andrew S Greene
Journal: Physiol Genomics Date: 2013-09-10 Impact factor: 3.107