| Literature DB >> 23196844 |
Jan-Wilhelm Kornfeld1, Jens C Brüning.
Abstract
Brown adipose tissue is intensively researched owing to its role in regulating energy and glucose homeostasis. Its differentiation is controlled through adrenergic-dependent regulation of the transcriptional co-regulator Prdm16. Adrenergic stimulation inhibits expression of miR-133a/b in a Mef2c-dependent manner to abrogate post-transcriptional silencing of Prdm16.Entities:
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Year: 2012 PMID: 23196844 DOI: 10.1038/ncb2642
Source DB: PubMed Journal: Nat Cell Biol ISSN: 1465-7392 Impact factor: 28.824