Literature DB >> 23196149

Aesthetics in synthesis and synthetic biology.

Steven A Benner1.   

Abstract

Physicists frequently allow aesthetics to guide their science. Chemists sometimes do. Biologists rarely do. They have encountered too frequently the consequences of the Darwinian 'hack'. The biological parts delivered by Darwinian processes are rarely simple, efficient, or elegant solutions to the biological problems that they address. Nevertheless, as humans, we seek to find aesthetics within our activities. In general, however, it is hard to distinguish what we say is beautiful from what is, in reality, utilitarian.
Copyright © 2012 Elsevier Ltd. All rights reserved.

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Year:  2012        PMID: 23196149      PMCID: PMC3805259          DOI: 10.1016/j.cbpa.2012.11.004

Source DB:  PubMed          Journal:  Curr Opin Chem Biol        ISSN: 1367-5931            Impact factor:   8.822


  4 in total

1.  The Art and Science of Total Synthesis at the Dawn of the Twenty-First Century.

Authors: 
Journal:  Angew Chem Int Ed Engl       Date:  2000-01       Impact factor: 15.336

2.  Creation of a bacterial cell controlled by a chemically synthesized genome.

Authors:  Daniel G Gibson; John I Glass; Carole Lartigue; Vladimir N Noskov; Ray-Yuan Chuang; Mikkel A Algire; Gwynedd A Benders; Michael G Montague; Li Ma; Monzia M Moodie; Chuck Merryman; Sanjay Vashee; Radha Krishnakumar; Nacyra Assad-Garcia; Cynthia Andrews-Pfannkoch; Evgeniya A Denisova; Lei Young; Zhi-Qing Qi; Thomas H Segall-Shapiro; Christopher H Calvey; Prashanth P Parmar; Clyde A Hutchison; Hamilton O Smith; J Craig Venter
Journal:  Science       Date:  2010-05-20       Impact factor: 47.728

3.  Recent advances in the chemistry of natural products.

Authors:  R B Woodward
Journal:  Pure Appl Chem       Date:  1968       Impact factor: 2.453

4.  Synthetic Biology, Tinkering Biology, and Artificial Biology. What are We Learning?

Authors:  Steven A Benner; Zunyi Yang; Fei Chen
Journal:  C R Chim       Date:  2010-08-07       Impact factor: 3.117

  4 in total
  8 in total

1.  On the Origin of the Canonical Nucleobases: An Assessment of Selection Pressures across Chemical and Early Biological Evolution.

Authors:  Andro C Rios; Yitzhak Tor
Journal:  Isr J Chem       Date:  2013-06       Impact factor: 3.333

2.  Mix and match backbones for the formation of H-bonded duplexes.

Authors:  Giulia Iadevaia; Alexander E Stross; Anja Neumann; Christopher A Hunter
Journal:  Chem Sci       Date:  2016-01-07       Impact factor: 9.825

3.  Homochiral oligomers with highly flexible backbones form stable H-bonded duplexes.

Authors:  Diego Núñez-Villanueva; Christopher A Hunter
Journal:  Chem Sci       Date:  2016-08-19       Impact factor: 9.825

4.  Backbone conformation affects duplex initiation and duplex propagation in hybridisation of synthetic H-bonding oligomers.

Authors:  Giulia Iadevaia; Diego Núñez-Villanueva; Alexander E Stross; Christopher A Hunter
Journal:  Org Biomol Chem       Date:  2018-06-06       Impact factor: 3.876

5.  H-Bonded Duplexes based on a Phenylacetylene Backbone.

Authors:  Jonathan A Swain; Giulia Iadevaia; Christopher A Hunter
Journal:  J Am Chem Soc       Date:  2018-09-04       Impact factor: 15.419

6.  Cooperative duplex formation by synthetic H-bonding oligomers.

Authors:  Alexander E Stross; Giulia Iadevaia; Christopher A Hunter
Journal:  Chem Sci       Date:  2015-10-22       Impact factor: 9.825

7.  Sequence-Selective Formation of Synthetic H-Bonded Duplexes.

Authors:  Alexander E Stross; Giulia Iadevaia; Diego Núñez-Villanueva; Christopher A Hunter
Journal:  J Am Chem Soc       Date:  2017-08-31       Impact factor: 15.419

8.  Mix and match recognition modules for the formation of H-bonded duplexes.

Authors:  Alexander E Stross; Giulia Iadevaia; Christopher A Hunter
Journal:  Chem Sci       Date:  2016-06-07       Impact factor: 9.825

  8 in total

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