Literature DB >> 23194431

Antabuse's diamond anniversary: still sparkling on?

Pete M Ellis1, Alan T Dronsfield.   

Abstract

Seventy-five years after its first medical use was described, disulfiram's place in treatment is being favourably re-evaluated. This paper reviews its discovery and subsequent development.
© 2012 Australasian Professional Society on Alcohol and other Drugs.

Keywords:  alcoholism; chemistry; disulfiram; history; psychotropic drugs

Mesh:

Substances:

Year:  2012        PMID: 23194431     DOI: 10.1111/dar.12018

Source DB:  PubMed          Journal:  Drug Alcohol Rev        ISSN: 0959-5236


  8 in total

1.  The Repurposed Drug Disulfiram Inhibits Urease and Aldehyde Dehydrogenase and Prevents In Vitro Growth of the Oomycete Pythium insidiosum.

Authors:  Theerapong Krajaejun; Tassanee Lohnoo; Wanta Yingyong; Thidarat Rujirawat; Yothin Kumsang; Passara Jongkhajornpong; Sirin Theerawatanasirikul; Weerayuth Kittichotirat; Onrapak Reamtong; Hanna Yolanda
Journal:  Antimicrob Agents Chemother       Date:  2019-07-25       Impact factor: 5.191

2.  Disulfiram-based disulfides as narrow-spectrum antibacterial agents.

Authors:  Jordan G Sheppard; Keely R Frazier; Pushkar Saralkar; Mohammad F Hossain; Werner J Geldenhuys; Timothy E Long
Journal:  Bioorg Med Chem Lett       Date:  2018-03-10       Impact factor: 2.823

3.  Disulfiram: A Repurposed Drug in Preclinical and Clinical Development for the Treatment of Infectious Diseases.

Authors:  Marco M Custodio; Jennifer Sparks; Timothy E Long
Journal:  Antiinfect Agents       Date:  2022-04-27

4.  Repurposing Thiram and Disulfiram as Antibacterial Agents for Multidrug-Resistant Staphylococcus aureus Infections.

Authors:  Timothy E Long
Journal:  Antimicrob Agents Chemother       Date:  2017-08-24       Impact factor: 5.191

5.  The role of interleukin-18 in glioblastoma pathology implies therapeutic potential of two old drugs-disulfiram and ritonavir.

Authors:  Richard E Kast
Journal:  Chin J Cancer       Date:  2015-04-09

6.  Redox effects and cytotoxic profiles of MJ25 and auranofin towards malignant melanoma cells.

Authors:  Marijke C C Sachweh; William C Stafford; Catherine J Drummond; Anna R McCarthy; Maureen Higgins; Johanna Campbell; Bertha Brodin; Elias S J Arnér; Sonia Laín
Journal:  Oncotarget       Date:  2015-06-30

7.  Oxidizing to death: disulfiram for cancer cell killing.

Authors:  Ansgar Brüning; Richard E Kast
Journal:  Cell Cycle       Date:  2014-04-22       Impact factor: 4.534

8.  Identification of small molecules targeting homoserine acetyl transferase from Mycobacterium tuberculosis and Staphylococcus aureus.

Authors:  Deepika Chaudhary; Avantika Singh; Mardiana Marzuki; Abhirupa Ghosh; Saqib Kidwai; Tannu Priya Gosain; Kiran Chawla; Sonu Kumar Gupta; Nisheeth Agarwal; Sudipto Saha; Yashwant Kumar; Krishan Gopal Thakur; Amit Singhal; Ramandeep Singh
Journal:  Sci Rep       Date:  2022-08-13       Impact factor: 4.996

  8 in total

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