| Literature DB >> 23192255 |
Stijn Deborggraeve1, Jian Yuan Dai, Yi Xiao, Hyongsok Tom Soh.
Abstract
We report a hybridization-based switching mechanism with single-base specificity that can be readily integrated with functional DNA nanostructures. As an exemplar, we have developed a switchable DNAzyme (SDZ) that only becomes activated in the presence of a perfectly matched trigger sequence and operates effectively at room temperature.Entities:
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Year: 2012 PMID： 23192255 PMCID： PMC3552611 DOI： 10.1039/c2cc36878a
Source DB: PubMed Journal: Chem Commun (Camb) ISSN： 1359-7345 Impact factor: 6.222