Literature DB >> 23190643

Dual-specificity phosphatases 2: surprising positive effect at the molecular level and a potential biomarker of diseases.

W Wei1, Y Jiao, A Postlethwaite, J M Stuart, Y Wang, D Sun, W Gu.   

Abstract

Dual-specificity phosphatases (DUSPs) is an emerging subclass of the protein tyrosine phosphatase gene superfamily, a heterogeneous group of protein phosphatases that can dephosphorylate both phosphotyrosine and phosphoserine/phosphothreonine residues within the one substrate. Recently, a series of investigations of DUSPs defined their essential roles in cell proliferation, cancer and the immune response. This review will focus on DUSP2, its involvement in different diseases and its potential as a therapeutic target.

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Year:  2012        PMID： 23190643     DOI： 10.1038/gene.2012.54

Source DB:  PubMed          Journal:  Genes Immun        ISSN： 1466-4879            Impact factor:   2.676


  20 in total

1.  The phosphatase DUSP2 controls the activity of the transcription activator STAT3 and regulates TH17 differentiation.

Authors:  Dan Lu; Liang Liu; Xin Ji; Yanan Gao; Xi Chen; Yu Liu; Yang Liu; Xuyang Zhao; Yan Li; Yunqiao Li; Yan Jin; Yu Zhang; Michael A McNutt; Yuxin Yin
Journal:  Nat Immunol       Date:  2015-10-19       Impact factor: 25.606

2.  Seasonal Variability and Shared Molecular Signatures of Inactivated Influenza Vaccination in Young and Older Adults.

Authors:  Stefan Avey; Subhasis Mohanty; Daniel G Chawla; Hailong Meng; Thilinie Bandaranayake; Ikuyo Ueda; Heidi J Zapata; Koonam Park; Tamara P Blevins; Sui Tsang; Robert B Belshe; Susan M Kaech; Albert C Shaw; Steven H Kleinstein
Journal:  J Immunol       Date:  2020-02-14       Impact factor: 5.422

3.  Impact of brief exercise on circulating monocyte gene and microRNA expression: implications for atherosclerotic vascular disease.

Authors:  Shlomit Radom-Aizik; Frank P Zaldivar; Fadia Haddad; Dan M Cooper
Journal:  Brain Behav Immun       Date:  2014-01-11       Impact factor: 7.217

4.  DUSP2 methylation is a candidate biomarker of outcome in head and neck cancer.

Authors:  Cristiana Lo Nigro; Daniela Vivenza; Nerina Denaro; Laura Lattanzio; Mirella Fortunato; Tim Crook; Marco Carlo Merlano
Journal:  Ann Transl Med       Date:  2018-07

5.  Bariatric Surgery Induces Disruption in Inflammatory Signaling Pathways Mediated by Immune Cells in Adipose Tissue: A RNA-Seq Study.

Authors:  Christine Poitou; Claire Perret; François Mathieu; Vinh Truong; Yuna Blum; Hervé Durand; Rohia Alili; Nadjim Chelghoum; Véronique Pelloux; Judith Aron-Wisnewsky; Adriana Torcivia; Jean-Luc Bouillot; Brian W Parks; Ewa Ninio; Karine Clément; Laurence Tiret
Journal:  PLoS One       Date:  2015-05-04       Impact factor: 3.240

6.  A Set of miRNAs, Their Gene and Protein Targets and Stromal Genes Distinguish Early from Late Onset ER Positive Breast Cancer.

Authors:  E P Bastos; H Brentani; C A B Pereira; A Polpo; L Lima; R D Puga; F S Pasini; C A B T Osorio; R A Roela; M I Achatz; A P Trapé; A M Gonzalez-Angulo; M M Brentani
Journal:  PLoS One       Date:  2016-05-06       Impact factor: 3.240

7.  Regulation of atypical MAP kinases ERK3 and ERK4 by the phosphatase DUSP2.

Authors:  Maria Perander; Rania Al-Mahdi; Thomas C Jensen; Jennifer A L Nunn; Hanne Kildalsen; Bjarne Johansen; Mads Gabrielsen; Stephen M Keyse; Ole-Morten Seternes
Journal:  Sci Rep       Date:  2017-03-02       Impact factor: 4.379

8.  Developmental cell programs are co-opted in inflammatory skin disease.

Authors:  Gary Reynolds; Peter Vegh; James Fletcher; Elizabeth F M Poyner; Emily Stephenson; Issac Goh; Rachel A Botting; Ni Huang; Bayanne Olabi; Anna Dubois; David Dixon; Kile Green; Daniel Maunder; Justin Engelbert; Mirjana Efremova; Krzysztof Polański; Laura Jardine; Claire Jones; Thomas Ness; Dave Horsfall; Jim McGrath; Christopher Carey; Dorin-Mirel Popescu; Simone Webb; Xiao-Nong Wang; Ben Sayer; Jong-Eun Park; Victor A Negri; Daria Belokhvostova; Magnus D Lynch; David McDonald; Andrew Filby; Tzachi Hagai; Kerstin B Meyer; Akhtar Husain; Jonathan Coxhead; Roser Vento-Tormo; Sam Behjati; Steven Lisgo; Alexandra-Chloé Villani; Jaume Bacardit; Philip H Jones; Edel A O'Toole; Graham S Ogg; Neil Rajan; Nick J Reynolds; Sarah A Teichmann; Fiona M Watt; Muzlifah Haniffa
Journal:  Science       Date:  2021-01-22       Impact factor: 47.728

9.  Anti-Metastatic and Anti-Angiogenic Effects of Curcumin Analog DK1 on Human Osteosarcoma Cells In Vitro.

Authors:  Muhammad Nazirul Mubin Aziz; Nurul Fattin Che Rahim; Yazmin Hussin; Swee Keong Yeap; Mas Jaffri Masarudin; Nurul Elyani Mohamad; Muhammad Nadeem Akhtar; Mohd Azuraidi Osman; Yoke Kqueen Cheah; Noorjahan Banu Alitheen
Journal:  Pharmaceuticals (Basel)       Date:  2021-06-03

10.  CONCORD biomarker prediction for novel drug introduction to different cancer types.

Authors:  Youngchul Kim; Patrick M Dillon; Taesung Park; Jae K Lee
Journal:  Oncotarget       Date:  2017-12-09
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