J Jiang1, S Kanthaswamy, J P Capitanio. 1. Department of Psychology and the California National Primate Research Center, University of California, Davis, CA 95616, USA. jngjiang@ucdavis.edu
Abstract
BACKGROUND: The use of Chinese-origin macaques in biomedical research is problematic for some scientists because of the reported behavioral and physiological differences from those of Indian origin. However, few studies have examined the effects of varying degrees of Chinese ancestry (DCA) on behavior, and they were typically based on small sample sizes and unusual rearing conditions. METHODS: Using data from a colony-wide program, we examined whether DCA was related to behavior and temperament ratings reflecting emotionality (fearfulness, aggression, and anxiety) and activity. The 249 subjects, born and reared in an outdoor social environment, were separated from their groups for a 25-h period of indoor testing. Their DCA (range: 0.6-99.4%) was determined by analyzing the frequency of short tandem repeat alleles. RESULTS AND CONCLUSIONS: The major effect of DCA was on fearfulness, with the more hybridized animals scoring lowest and the more pure Indian- and Chinese-origin macaques resembling each other.
BACKGROUND: The use of Chinese-origin macaques in biomedical research is problematic for some scientists because of the reported behavioral and physiological differences from those of Indian origin. However, few studies have examined the effects of varying degrees of Chinese ancestry (DCA) on behavior, and they were typically based on small sample sizes and unusual rearing conditions. METHODS: Using data from a colony-wide program, we examined whether DCA was related to behavior and temperament ratings reflecting emotionality (fearfulness, aggression, and anxiety) and activity. The 249 subjects, born and reared in an outdoor social environment, were separated from their groups for a 25-h period of indoor testing. Their DCA (range: 0.6-99.4%) was determined by analyzing the frequency of short tandem repeat alleles. RESULTS AND CONCLUSIONS: The major effect of DCA was on fearfulness, with the more hybridized animals scoring lowest and the more pure Indian- and Chinese-origin macaques resembling each other.
Authors: Binhua Ling; Ronald S Veazey; Amara Luckay; Cecilia Penedo; Keyu Xu; Jeffrey D Lifson; Preston A Marx Journal: AIDS Date: 2002-07-26 Impact factor: 4.177
Authors: Genesio M Karere; Erin L Kinnally; Jessica N Sanchez; Thomas R Famula; Leslie A Lyons; John P Capitanio Journal: Biol Psychiatry Date: 2008-12-21 Impact factor: 13.382
Authors: S Kanthaswamy; L Gill; J Satkoski; V Goyal; V Malladi; A Kou; K Basuta; L Sarkisyan; D George; D G Smith Journal: J Med Primatol Date: 2008-08-18 Impact factor: 0.667
Authors: G L Fawcett; A M Dettmer; D Kay; M Raveendran; J D Higley; N D Ryan; J L Cameron; J Rogers Journal: Int J Primatol Date: 2014-02-01 Impact factor: 2.264
Authors: Dharmendra B Goswami; Lisa M Ogawa; Joshua M Ward; Gregory M Miller; Eric J Vallender Journal: BMC Genomics Date: 2013-10-11 Impact factor: 3.969