| Literature DB >> 2318301 |
J Stackhouse1, S R Presnell, G M McGeehan, K P Nambiar, S A Benner.
Abstract
The sequence of the ribonuclease from the ancestor of swamp buffalo, river buffalo, and ox, corresponding approximately to Pachyportax latidens, an extinct ruminant known from the fossil record, has been reconstructed using the rule of 'maximum parsimony'. This protein and two sequences that may have been intermediates in the evolution of modern ribonuclease have been constructed in the laboratory by site-directed mutagenesis, and their properties examined.Entities:
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Year: 1990 PMID： 2318301 DOI： 10.1016/0014-5793(90)80164-e
Source DB: PubMed Journal: FEBS Lett ISSN： 0014-5793 Impact factor: 4.124