Literature DB >> 23174065

The effect of core and epitendinous suture modifications on repair of intrasynovial flexor tendons in an in vivo canine model.

Duretti T Fufa1, Daniel A Osei, Ryan P Calfee, Matthew J Silva, Stavros Thomopoulos, Richard H Gelberman.   

Abstract

PURPOSE: To determine in vivo effects of modifications to core and epitendinous suture techniques in a canine intrasynovial flexor tendon repair model using clinically relevant rehabilitation. Our null hypothesis was that gap formation and rupture rates would remain consistent across repair techniques.
METHODS: We evaluated gap formation and rupture in 75 adult mongrel dogs that underwent repair of intrasynovial flexor tendon lacerations followed by standardized postoperative therapy. The current suture technique was a 4-0, 8-strand core suture with a purchase of 1.2 cm and a 5-0, epitendinous suture repair with a 2-mm purchase length and depth. We compared gap and failure by chi-square analysis to a historical group of in vivo repairs (n = 76) from the same canine model using 8-strand core suture repair with purchase of 0.75 cm and 6-0 epitendinous suture with a 1-mm purchase length and depth.
RESULTS: A total of 93% of tendons (n = 70) demonstrated gapping of less than 3 mm using the current suture technique. Five percent of tendons (n = 4) had a gap of 3 mm or greater, and there was 1 repair site failure. This was significantly improved over the comparison group of historical 8-strand core repair technique, which resulted in 82% (n = 62) of repairs with a gap of less than 3 mm and 7 failures (9%).
CONCLUSIONS: In an in vivo model, current modifications to suture techniques for intrasynovial flexor tendon repair demonstrated significant improvements in gap formation and rupture compared with a similar technique using shorter purchase lengths and shallower purchase depth. CLINICAL RELEVANCE: Suggested repair modifications for the treatment of zone II flexor tendon transections demonstrate improvements in gap formation and tendon rupture in vivo.
Copyright © 2012 American Society for Surgery of the Hand. Published by Elsevier Inc. All rights reserved.

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Year:  2012        PMID: 23174065      PMCID: PMC3513918          DOI: 10.1016/j.jhsa.2012.09.012

Source DB:  PubMed          Journal:  J Hand Surg Am        ISSN: 0363-5023            Impact factor:   2.230


  19 in total

1.  Tendon healing within the flexor digital sheath in the dog.

Authors:  A D POTENZA
Journal:  J Bone Joint Surg Am       Date:  1962-01       Impact factor: 5.284

2.  Effects of tension across the tendon repair site on tendon gap and ultimate strength.

Authors:  Ya Fang Wu; Jin Bo Tang
Journal:  J Hand Surg Am       Date:  2012-03-02       Impact factor: 2.230

3.  Total and intrasynovial work of flexion of human cadaver flexor digitorum profundus tendons after modified Kessler and MGH repair techniques.

Authors:  Chao Yang; Chunfeng Zhao; Peter C Amadio; Tatsuro Tanaka; Kristin D Zhao; Kai-Nan An
Journal:  J Hand Surg Am       Date:  2005-05       Impact factor: 2.230

4.  Effect of peripheral suture depth on strength of tendon repairs.

Authors:  E Diao; J S Hariharan; O Soejima; J C Lotz
Journal:  J Hand Surg Am       Date:  1996-03       Impact factor: 2.230

5.  The effects of multiple-strand suture methods on the strength and excursion of repaired intrasynovial flexor tendons: a biomechanical study in dogs.

Authors:  S C Winters; R H Gelberman; S L Woo; S S Chan; R Grewal; J G Seiler
Journal:  J Hand Surg Am       Date:  1998-01       Impact factor: 2.230

6.  Biomechanical and histologic characteristics of canine flexor tendon repair using early postoperative mobilization.

Authors:  M Aoki; H Kubota; D L Pruitt; P R Manske
Journal:  J Hand Surg Am       Date:  1997-01       Impact factor: 2.230

7.  Intrasynovial flexor tendon repair. An experimental study comparing low and high levels of in vivo force during rehabilitation in canines.

Authors:  M I Boyer; R H Gelberman; M E Burns; H Dinopoulos; R Hofem; M J Silva
Journal:  J Bone Joint Surg Am       Date:  2001-06       Impact factor: 5.284

8.  The effect of gap formation at the repair site on the strength and excursion of intrasynovial flexor tendons. An experimental study on the early stages of tendon-healing in dogs.

Authors:  R H Gelberman; M I Boyer; M D Brodt; S C Winters; M J Silva
Journal:  J Bone Joint Surg Am       Date:  1999-07       Impact factor: 5.284

9.  Intrasynovial flexor tendon repair: a biomechanical study of variations in suture application in human cadavera.

Authors:  Gregory N Nelson; Ryan Potter; Eleni Ntouvali; Matthew J Silva; Martin I Boyer; Richard H Gelberman; Stavros Thomopoulos
Journal:  J Orthop Res       Date:  2012-03-27       Impact factor: 3.494

10.  Digital resistance and tendon strength during the first week after flexor digitorum profundus tendon repair in a canine model in vivo.

Authors:  Chunfeng Zhao; Peter C Amadio; Philippe Paillard; Tatsuro Tanaka; Mark E Zobitz; Dirk R Larson; Kai-Nan An
Journal:  J Bone Joint Surg Am       Date:  2004-02       Impact factor: 5.284

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  7 in total

1.  Cell and Biologic-Based Treatment of Flexor Tendon Injuries.

Authors:  Stephen W Linderman; Richard H Gelberman; Stavros Thomopoulos; Hua Shen
Journal:  Oper Tech Orthop       Date:  2016-09

2.  Shear lag sutures: Improved suture repair through the use of adhesives.

Authors:  Stephen W Linderman; Ioannis Kormpakis; Richard H Gelberman; Victor Birman; Ulrike G K Wegst; Guy M Genin; Stavros Thomopoulos
Journal:  Acta Biomater       Date:  2015-05-25       Impact factor: 8.947

3.  Improving Strength and Quality of Epitendinous Repairs.

Authors:  Angel Farinas; Michael Stephanides; Steven Schneeberger; Alonda Pollins; Nancy Cardwell; Wesley P Thayer
Journal:  Hand (N Y)       Date:  2018-12-05

4.  The effect of suture caliber and number of core suture strands on zone II flexor tendon repair: a study in human cadavers.

Authors:  Daniel A Osei; Jeffrey G Stepan; Ryan P Calfee; Stavros Thomopoulos; Martin I Boyer; Ryan Potter; Richard H Gelberman
Journal:  J Hand Surg Am       Date:  2013-12-15       Impact factor: 2.230

Review 5.  The role of animal models in tendon research.

Authors:  M W Hast; A Zuskov; L J Soslowsky
Journal:  Bone Joint Res       Date:  2014-06       Impact factor: 5.853

6.  Enhanced Zone II Flexor Tendon Repair through a New Half Hitch Loop Suture Configuration.

Authors:  Ioannis Kormpakis; Stephen W Linderman; Stavros Thomopoulos; Richard H Gelberman
Journal:  PLoS One       Date:  2016-04-21       Impact factor: 3.240

7.  An In Vivo Comparison: Novel Mesh Suture Versus Traditional Suture-Based Repair in a Rabbit Tendon Model.

Authors:  Lindsay E Janes; Lauren M Mioton; Megan E Fracol; Jason H Ko
Journal:  J Hand Surg Glob Online       Date:  2021-11-19
  7 in total

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