Literature DB >> 23169388

An efficient single-enzymatic cascade for asymmetric synthesis of chiral amines catalyzed by ω-transaminase.

Bo Wang1, Henrik Land, Per Berglund.   

Abstract

An efficient single-enzymatic cascade approach for the asymmetric synthesis of chiral amines has been developed, which applies the amino donor 3-aminocyclohexa-1,5-dienecarboxylic acid spontaneously tautomerizing to reach reaction completion with excellent ee values.

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Year:  2012        PMID： 23169388     DOI： 10.1039/c2cc37232k

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN： 1359-7345            Impact factor:   6.222


  8 in total

1.  Asymmetric Preparation of prim-, sec-, and tert-Amines Employing Selected Biocatalysts.

Authors:  Wolfgang Kroutil; Eva-Maria Fischereder; Christine S Fuchs; Horst Lechner; Francesco G Mutti; Desiree Pressnitz; Aashrita Rajagopalan; Johann H Sattler; Robert C Simon; Elina Siirola
Journal:  Org Process Res Dev       Date:  2013-04-22       Impact factor: 3.317

2.  trans-Symmetric Dynamic Covalent Systems: Connected Transamination and Transimination Reactions.

Authors:  Fredrik Schaufelberger; Lei Hu; Olof Ramström
Journal:  Chemistry       Date:  2015-06-03       Impact factor: 5.236

3.  Chiral amine synthesis using ω-transaminases: an amine donor that displaces equilibria and enables high-throughput screening.

Authors:  Anthony P Green; Nicholas J Turner; Elaine O'Reilly
Journal:  Angew Chem Int Ed Engl       Date:  2014-08-19       Impact factor: 15.336

4.  Amine dehydrogenases: efficient biocatalysts for the reductive amination of carbonyl compounds.

Authors:  Tanja Knaus; Wesley Böhmer; Francesco G Mutti
Journal:  Green Chem       Date:  2017-01-21       Impact factor: 10.182

5.  Transaminase-Catalyzed Racemization with Potential for Dynamic Kinetic Resolutions.

Authors:  Federica Ruggieri; Luuk M van Langen; Derek T Logan; Björn Walse; Per Berglund
Journal:  ChemCatChem       Date:  2018-10-11       Impact factor: 5.686

6.  Parallel Interconnected Kinetic Asymmetric Transformation (PIKAT) with an Immobilized ω-Transaminase in Neat Organic Solvent.

Authors:  Wesley Böhmer; Lucien Koenekoop; Timothée Simon; Francesco G Mutti
Journal:  Molecules       Date:  2020-05-03       Impact factor: 4.411

Review 7.  Biocatalytic Reduction Reactions from a Chemist's Perspective.

Authors:  Frank Hollmann; Diederik J Opperman; Caroline E Paul
Journal:  Angew Chem Int Ed Engl       Date:  2020-11-03       Impact factor: 15.336

8.  High Regio- and Stereoselective Multi-enzymatic Synthesis of All Phenylpropanolamine Stereoisomers from β-Methylstyrene.

Authors:  Maria L Corrado; Tanja Knaus; Francesco G Mutti
Journal:  Chembiochem       Date:  2021-05-13       Impact factor: 3.164
  8 in total

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