Literature DB >> 23166250

Complete genome sequence of Klebsiella pneumoniae phage JD001.

Zelin Cui1, Wenbin Shen, Zheng Wang, Haotian Zhang, Rao Me, Yanchun Wang, Lingbin Zeng, Yongzhang Zhu, Jinhong Qin, Ping He, Xiaokui Guo.   

Abstract

Klebsiella pneumoniae is a member of the family Enterobacteriaceae, opportunistic pathogens that are among the eight most prevalent infectious agents in hospitals. The emergence of multidrug-resistant strains of K. pneumoniae has became a public health problem globally. To develop an effective antimicrobial agent, we isolated a bacteriophage, named JD001, from seawater and sequenced its genome. Comparative genome analysis of phage JD001 with other K. pneumoniae bacteriophages revealed that phage JD001 has little similarity to previously published K. pneumoniae phages KP15, KP32, KP34, and phiKO2. Here we announce the complete genome sequence of JD001 and report major findings from the genomic analysis.

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Year:  2012        PMID: 23166250      PMCID: PMC3503054          DOI: 10.1128/JVI.02435-12

Source DB:  PubMed          Journal:  J Virol        ISSN: 0022-538X            Impact factor:   5.103


  10 in total

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  9 in total

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