PURPOSE: To determine clinical characteristics and rate of ocular complications in patients with Vogt-Koyanagi-Harada disease (VKH). METHODS: The authors performed a retrospective review of 48 consecutive patients (92 affected eyes) diagnosed with VKH. Demographic data, clinical manifestations, treatment modalities, and ocular complications were registered. RESULTS: VKH constituted approximately 10% of all new encounters of uveitis patients. Ocular complications developed in 49/92 (53%) eyes. The most frequent complication was cataract (45%), followed by glaucoma (29%). The presence of ocular complications was not associated with stage of the disease at presentation (p = .654) or the treatment modalities (p = .261). Recurrent inflammation developed in 13% and was not associated with initial intravenous corticosteroids or use of immunosuppressive drugs (p = .614 and p = 1.000). CONCLUSIONS: Cataract and glaucoma represented the common ocular complications of VKH. Recurrences developed solely in 13% of patients and were not associated with a specific treatment regimen but with an early withdrawal of systemic corticosteroids.
PURPOSE: To determine clinical characteristics and rate of ocular complications in patients with Vogt-Koyanagi-Harada disease (VKH). METHODS: The authors performed a retrospective review of 48 consecutive patients (92 affected eyes) diagnosed with VKH. Demographic data, clinical manifestations, treatment modalities, and ocular complications were registered. RESULTS:VKH constituted approximately 10% of all new encounters of uveitispatients. Ocular complications developed in 49/92 (53%) eyes. The most frequent complication was cataract (45%), followed by glaucoma (29%). The presence of ocular complications was not associated with stage of the disease at presentation (p = .654) or the treatment modalities (p = .261). Recurrent inflammation developed in 13% and was not associated with initial intravenous corticosteroids or use of immunosuppressive drugs (p = .614 and p = 1.000). CONCLUSIONS:Cataract and glaucoma represented the common ocular complications of VKH. Recurrences developed solely in 13% of patients and were not associated with a specific treatment regimen but with an early withdrawal of systemic corticosteroids.
Authors: Carlos Alvarez-Guzman; Jorge E Valdez-Garcia; Raul E Ruiz-Lozano; Alejandro Rodriguez-Garcia; Carlos F Navas-Villar; Curt Hartleben-Matkin; Miguel Pedroza-Seres Journal: Int Ophthalmol Date: 2022-07-05 Impact factor: 2.031
Authors: Alireza Hedayatfar; Sana Khochtali; Moncef Khairallah; Masaru Takeuchi; Ahmed Abu El Asrar; Carl P Herbort Journal: J Curr Ophthalmol Date: 2018-12-13