Literature DB >> 23163276

Lipofuscin and the principles of fundus autofluorescence: a review.

Namrata Nandakumar1, Sheldon Buzney, John J Weiter.   

Abstract

Fundus autofluorescence is a non-invasive imaging modality that measures lipofuscin that has accumulated in the retinal pigment epithelium (RPE). Excessive lipofuscin in the RPE is a common pathway found in several diseases including Stargardt's disease and age-related macular degeneration. This review discusses the role of photooxidative damage in the development of lipofuscin and the principles of fundus autofluorescence.

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Year:  2012        PMID： 23163276     DOI： 10.3109/08820538.2012.711415

Source DB:  PubMed          Journal:  Semin Ophthalmol        ISSN： 0882-0538            Impact factor:   1.975


  11 in total

1.  [Avoiding mistakes in anti-VEGF intravitreal injection therapy].

Authors:  Carsten Framme; Bernd Junker; Nicolas Feltgen; Hans Hoerauf; Nina-Antonia Striebe; Joachim Wachtlin; Ingo Volkmann
Journal:  Ophthalmologe       Date:  2022-01-14       Impact factor: 1.059

2.  Macular optical coherence tomography findings and GPR143 mutations in patients with ocular albinism.

Authors:  H E Sepúlveda-Vázquez; C Villanueva-Mendoza; J C Zenteno; V Villegas-Ruiz; E Pelcastre-Luna; G García-Aguirre
Journal:  Int Ophthalmol       Date:  2014-02-14       Impact factor: 2.031

3.  Fundus Autofluorescence Change as an Early Indicator of Treatment Effect of Brachytherapy for Choroidal Melanomas.

Authors:  Jesintha Navaratnam; Thomas P Bærland; Nils A Eide; Rowan T Faber; Bernt L Rekstad; Demetrios G Vavvas; Ragnheiður Bragadóttir
Journal:  Ocul Oncol Pathol       Date:  2019-05-16

4.  Widespread choroidal thickening and abnormal midperipheral fundus autofluorescence characterize exudative age-related macular degeneration with choroidal vascular hyperpermeability.

Authors:  Yoko Nomura; Hidenori Takahashi; Xue Tan; Ryo Obata; Yasuo Yanagi
Journal:  Clin Ophthalmol       Date:  2015-02-11

Review 5.  Autofluorescence spectroscopy and imaging: a tool for biomedical research and diagnosis.

Authors:  A C Croce; G Bottiroli
Journal:  Eur J Histochem       Date:  2014-12-12       Impact factor: 3.188

6.  Clinical, optical coherence tomography, and fundus autofluorescence findings in patients with intraocular tumors.

Authors:  Daniel Samuelsson; Monika Sznage; Karl Engelsberg; Elisabeth Wittström
Journal:  Clin Ophthalmol       Date:  2016-10-07

7.  Inhibition or Stimulation of Autophagy Affects Early Formation of Lipofuscin-Like Autofluorescence in the Retinal Pigment Epithelium Cell.

Authors:  Lei Lei; Radouil Tzekov; Huapeng Li; J Hugh McDowell; Guangping Gao; W Clay Smith; Shibo Tang; Shalesh Kaushal
Journal:  Int J Mol Sci       Date:  2017-03-29       Impact factor: 5.923

8.  Grand challenges in cellular biochemistry: the "next-gen" biochemistry.

Authors:  Cecilia Giulivi
Journal:  Front Chem       Date:  2014-04-29       Impact factor: 5.221

9.  The EMIF-AD PreclinAD study: study design and baseline cohort overview.

Authors:  Elles Konijnenberg; Stephen F Carter; Mara Ten Kate; Anouk den Braber; Jori Tomassen; Chinenye Amadi; Linda Wesselman; Hoang-Ton Nguyen; Jacoba A van de Kreeke; Maqsood Yaqub; Matteo Demuru; Sandra D Mulder; Arjan Hillebrand; Femke H Bouwman; Charlotte E Teunissen; Erik H Serné; Annette C Moll; Frank D Verbraak; Rainer Hinz; Neil Pendleton; Adriaan A Lammertsma; Bart N M van Berckel; Frederik Barkhof; Dorret I Boomsma; Philip Scheltens; Karl Herholz; Pieter Jelle Visser
Journal:  Alzheimers Res Ther       Date:  2018-08-04       Impact factor: 6.982

Review 10.  The Use of Fundus Autofluorescence in Dry Age-Related Macular Degeneration

Authors:  Nedime Şahinoğlu Keşkek; Figen Şermet
Journal:  Turk J Ophthalmol       Date:  2021-06-29
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