Literature DB >> 23161559

Imaging mass spectrometry and genome mining reveal highly antifungal virulence factor of mushroom soft rot pathogen.

Katharina Graupner1, Kirstin Scherlach, Tom Bretschneider, Gerald Lackner, Martin Roth, Harald Gross, Christian Hertweck.   

Abstract

Caught in the act: imaging mass spectrometry of a button mushroom infected with the soft rot pathogen Janthinobacterium agaricidamnosum in conjunction with genome mining revealed jagaricin as a highly antifungal virulence factor that is not produced under standard cultivation conditions. The structure of jagaricin was rigorously elucidated by a combination of physicochemical analyses, chemical derivatization, and bioinformatics.
Copyright © 2012 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Entities:  

Mesh：

Substances：

Year:  2012        PMID： 23161559     DOI： 10.1002/anie.201206658

Source DB:  PubMed          Journal:  Angew Chem Int Ed Engl        ISSN： 1433-7851            Impact factor:   15.336


  12 in total

Review 1.  Recent advances in natural product discovery.

Authors:  Yunzi Luo; Ryan E Cobb; Huimin Zhao
Journal:  Curr Opin Biotechnol       Date:  2014-09-26       Impact factor: 9.740

Review 2.  Mass spectrometry tools and workflows for revealing microbial chemistry.

Authors:  Tal Luzzatto-Knaan; Alexey V Melnik; Pieter C Dorrestein
Journal:  Analyst       Date:  2015-08-07       Impact factor: 4.616

3.  Analytical chemistry: Virulence caught green-handed.

Authors:  Laura M Sanchez; Pieter C Dorrestein
Journal:  Nat Chem       Date:  2013-03       Impact factor: 24.427

Review 4.  Mass spectrometry of natural products: current, emerging and future technologies.

Authors:  Amina Bouslimani; Laura M Sanchez; Neha Garg; Pieter C Dorrestein
Journal:  Nat Prod Rep       Date:  2014-05-07       Impact factor: 13.423

5.  Genome Sequence of Mushroom Soft-Rot Pathogen Janthinobacterium agaricidamnosum.

Authors:  Katharina Graupner; Gerald Lackner; Christian Hertweck
Journal:  Genome Announc       Date:  2015-04-16

6.  Microbial communication leading to the activation of silent fungal secondary metabolite gene clusters.

Authors:  Tina Netzker; Juliane Fischer; Jakob Weber; Derek J Mattern; Claudia C König; Vito Valiante; Volker Schroeckh; Axel A Brakhage
Journal:  Front Microbiol       Date:  2015-04-20       Impact factor: 5.640

7.  Antagonistic bacteria disrupt calcium homeostasis and immobilize algal cells.

Authors:  Prasad Aiyar; Daniel Schaeme; María García-Altares; David Carrasco Flores; Hannes Dathe; Christian Hertweck; Severin Sasso; Maria Mittag
Journal:  Nat Commun       Date:  2017-11-24       Impact factor: 14.919

8.  Metabolomics: Eavesdropping on silent conversations between hosts and their unwelcome guests.

Authors:  Sydney N Newsom; Laura-Isobel McCall
Journal:  PLoS Pathog       Date:  2018-04-05       Impact factor: 6.823

9.  Draft Genome Sequence of Janthinobacterium sp. Strain PC23-8, Isolated from a Freshwater Stream Impacted by Acid Mine Drainage.

Authors:  Caitlin E Clark; Matthew G Banyas; Stephen E Noell; David A Essig
Journal:  Microbiol Resour Announc       Date:  2019-10-10

10.  Genomic Characterisation of Mushroom Pathogenic Pseudomonads and Their Interaction with Bacteriophages.

Authors:  Nathaniel Storey; Mojgan Rabiey; Benjamin W Neuman; Robert W Jackson; Geraldine Mulley
Journal:  Viruses       Date:  2020-11-10       Impact factor: 5.048
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.