Literature DB >> 23160355

Epigenetics: a new link toward understanding human disease and drug response.

A M Cressman1, M Piquette-Miller.   

Abstract

Molecular medicine is moving beyond genomics to encompass the new scientific field of epigenetics. First described as a conceptual model of how genes might interact with their surroundings to produce a phenotype, epigenomic research currently investigates mechanisms of nongenetic modification contributing to gene regulation and examines the impact of these changes on human health and behavior.

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Year:  2012        PMID: 23160355     DOI: 10.1038/clpt.2012.179

Source DB:  PubMed          Journal:  Clin Pharmacol Ther        ISSN: 0009-9236            Impact factor:   6.875


  3 in total

1.  The fiduciary relationship model for managing clinical genomic "incidental" findings.

Authors:  Gabriel Lázaro-Muñoz
Journal:  J Law Med Ethics       Date:  2014       Impact factor: 1.718

2.  Key Challenges in the Search for Innovative Drug Treatments for Special Populations. Converging Needs in Neonatology, Pediatrics, and Medical Genetics.

Authors:  Stuart MacLeod
Journal:  Children (Basel)       Date:  2017-08-04

Review 3.  The importance of early life in childhood obesity and related diseases: a report from the 2014 Gravida Strategic Summit.

Authors:  E C Macaulay; E L Donovan; M P Leask; F H Bloomfield; M H Vickers; P K Dearden; P N Baker
Journal:  J Dev Orig Health Dis       Date:  2014-10-13       Impact factor: 2.401

  3 in total

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