Literature DB >> 23159445

Diagnostic opportunities based on skin biomarkers.

Sumit Paliwal1, Byeong Hee Hwang, Kenneth Y Tsai, Samir Mitragotri.   

Abstract

Systemic as well as localized skin diseases modify the molecular composition of human skin. Changes in skin chemistry have been observed in diseases such as cancer, psoriasis, eczema, diabetes, and atherosclerosis. Skin chemistry, represented by an enormous wealth of disease biomarkers including lipids, structural proteins, inflammatory mediators, nucleic acids and small molecules, therefore, can serve as a "window to body's health". Various methods including tape-stripping, iontophoresis, microneedles and ultrasound, among others, are being developed to access skin biomarkers and understand skin's detailed molecular composition. This information provides opportunities to diagnose various diseases and their response to therapeutic treatments. This review provides an overview of such diagnostic and theranostic opportunities.
Copyright © 2012 Elsevier B.V. All rights reserved.

Entities:  

Keywords:  Biochemistry; Biomarkers; Diagnostics; Non-invasive; Skin

Mesh：

Substances：

Year:  2012        PMID： 23159445     DOI： 10.1016/j.ejps.2012.10.009

Source DB:  PubMed          Journal:  Eur J Pharm Sci        ISSN： 0928-0987            Impact factor:   4.384


  18 in total

1.  Optimized lysis buffer reagents for solubilization and preservation of proteins from cells and tissues.

Authors:  Byeong Hee Hwang; Kenneth Y Tsai; Samir Mitragotri
Journal:  Drug Deliv Transl Res       Date:  2013-10       Impact factor: 4.617

2.  Improved immunogenicity of individual influenza vaccine components delivered with a novel dissolving microneedle patch stable at room temperature.

Authors:  Elena V Vassilieva; Haripriya Kalluri; Devin McAllister; Misha T Taherbhai; E Stein Esser; Winston P Pewin; Joanna A Pulit-Penaloza; Mark R Prausnitz; Richard W Compans; Ioanna Skountzou
Journal:  Drug Deliv Transl Res       Date:  2015-08       Impact factor: 4.617

3.  Oral Biologic Delivery: Advances Toward Oral Subunit, DNA, and mRNA Vaccines and the Potential for Mass Vaccination During Pandemics.

Authors:  Jacob William Coffey; Gaurav Das Gaiha; Giovanni Traverso
Journal:  Annu Rev Pharmacol Toxicol       Date:  2020-08-31       Impact factor: 13.820

4.  Collection of analytes from microneedle patches.

Authors:  Andrey V Romanyuk; Vasiliy N Zvezdin; Pradnya Samant; Mark I Grenader; Marina Zemlyanova; Mark R Prausnitz
Journal:  Anal Chem       Date:  2014-10-17       Impact factor: 6.986

5.  Application of sebomics for the analysis of residual skin surface components to detect potential biomarkers of type-1 diabetes mellitus.

Authors:  Satyajit S Shetage; Matthew J Traynor; Marc B Brown; Thomas M Galliford; Robert P Chilcott
Journal:  Sci Rep       Date:  2017-08-21       Impact factor: 4.379

6.  Rapid, low cost prototyping of transdermal devices for personal healthcare monitoring.

Authors:  Sanjiv Sharma; Anwer Saeed; Christopher Johnson; Nikolaj Gadegaard; Anthony Eg Cass
Journal:  Sens Biosensing Res       Date:  2017-04

7.  Hydrogel Microfilaments toward Intradermal Health Monitoring.

Authors:  Nalin Tejavibulya; David A M Colburn; Francis A Marcogliese; Kyung-Ae Yang; Vincent Guo; Shilpika Chowdhury; Milan N Stojanovic; Samuel K Sia
Journal:  iScience       Date:  2019-10-23

Review 8.  Microneedle-based devices for point-of-care infectious disease diagnostics.

Authors:  Rachael V Dixon; Eldhose Skaria; Wing Man Lau; Philip Manning; Mark A Birch-Machin; S Moein Moghimi; Keng Wooi Ng
Journal:  Acta Pharm Sin B       Date:  2021-02-16       Impact factor: 11.413

9.  Proteogenomic analysis of psoriasis reveals discordant and concordant changes in mRNA and protein abundance.

Authors:  William R Swindell; Henriette A Remmer; Mrinal K Sarkar; Xianying Xing; Drew H Barnes; Liza Wolterink; John J Voorhees; Rajan P Nair; Andrew Johnston; James T Elder; Johann E Gudjonsson
Journal:  Genome Med       Date:  2015-08-04       Impact factor: 11.117

10.  The kin17 Protein in Murine Melanoma Cells.

Authors:  Anelise C Ramos; Vanessa P Gaspar; Sabrina M G Kelmer; Tarciso A Sellani; Ana G U Batista; Quirino A De Lima Neto; Elaine G Rodrigues; Maria A Fernandez
Journal:  Int J Mol Sci       Date:  2015-11-24       Impact factor: 5.923
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