Literature DB >> 23152330

Phosphoinositide pathway and the signal transduction network in neural development.

Vincenza Rita Lo Vasco1.   

Abstract

The development of the nervous system is under the strict control of a number of signal transduction pathways, often interconnected. Among them, the phosphoinositide (PI) pathway and the related phospholipase C (PI-PLC) family of enzymes have been attracting much attention. Besides their well-known role in the regulation of intracellular calcium levels, PI-PLC enzymes interact with a number of molecules belonging to further signal transduction pathways, contributing to a specific and complex network in the developing nervous system. In this review, the connections of PI signalling with further transduction pathways acting during neural development are discussed, with special regard to the role of the PI-PLC family of enzymes.

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Year:  2012        PMID： 23152330      PMCID： PMC5561820          DOI： 10.1007/s12264-012-1283-x

Source DB:  PubMed          Journal:  Neurosci Bull        ISSN： 1995-8218            Impact factor:   5.203


  106 in total

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2.  Phosphoinositide-specific Phospholipase C β1 gene deletion in bipolar disorder affected patient.

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3.  Neuropeptide Y reduces the expression of PLCB2, PLCD1 and selected PLC genes in cultured human endothelial cells.

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4.  Lypopolysaccharide downregulates the expression of selected phospholipase C genes in cultured endothelial cells.

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Journal:  Inflammation       Date:  2013-08       Impact factor: 4.092

5.  Ezrin silencing remodulates the expression of Phosphoinositide-specific Phospholipase C enzymes in human osteosarcoma cell lines.

Authors:  V R Lo Vasco; M Leopizzi; C Puggioni; C Della Rocca
Journal:  J Cell Commun Signal       Date:  2014-07-30       Impact factor: 5.782

6.  Associations Between Behavioral Effects of Bisphenol A and DNA Methylation in Zebrafish Embryos.

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8.  Functional enrichment analysis based on long noncoding RNA associations.

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  8 in total

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