Literature DB >> 23149298

Synthesis of fluorescent ristocetin aglycon derivatives with remarkable antibacterial and antiviral activities.

Attila Sipos1, Gábor Máté, Erzsébet Rőth, Anikó Borbás, Gyula Batta, Ilona Bereczki, Sándor Kéki, István Jóna, Eszter Ostorházi, Ferenc Rozgonyi, Evelien Vanderlinden, Lieve Naesens, Pál Herczegh.   

Abstract

Isoindole and benzoisoindole derivatives of ristocetin aglycon have been prepared by reaction with o-phthalaldehyde or naphthalene-2,3-dialdehyde and various thiols. The new compounds exhibited potent antibacterial and anti-influenza virus activity. The cluster forming and fluorescent properties of the aglycon derivatives were also studied.
Copyright © 2012 Elsevier Masson SAS. All rights reserved.

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Year:  2012        PMID： 23149298     DOI： 10.1016/j.ejmech.2012.10.030

Source DB:  PubMed          Journal:  Eur J Med Chem        ISSN： 0223-5234            Impact factor:   6.514


  3 in total

1.  Synthesis and antibacterial evaluation of some teicoplanin pseudoaglycon derivatives containing alkyl- and arylthiosubstituted maleimides.

Authors:  Magdolna Csávás; Adrienn Miskovics; Zsolt Szűcs; Erzsébet Rőth; Zsolt L Nagy; Ilona Bereczki; Mihály Herczeg; Gyula Batta; Éva Nemes-Nikodém; Eszter Ostorházi; Ferenc Rozgonyi; Anikó Borbás; Pál Herczegh
Journal:  J Antibiot (Tokyo)       Date:  2015-04-01       Impact factor: 2.649

2.  Structure-activity relationship studies of lipophilic teicoplanin pseudoaglycon derivatives as new anti-influenza virus agents.

Authors:  Zsolt Szűcs; Viktor Kelemen; Son Le Thai; Magdolna Csávás; Erzsébet Rőth; Gyula Batta; Annelies Stevaert; Evelien Vanderlinden; Lieve Naesens; Pál Herczegh; Anikó Borbás
Journal:  Eur J Med Chem       Date:  2018-08-22       Impact factor: 6.514

3.  Reprogramming of the Antibacterial Drug Vancomycin Results in Potent Antiviral Agents Devoid of Antibacterial Activity.

Authors:  Zsolt Szűcs; Lieve Naesens; Annelies Stevaert; Eszter Ostorházi; Gyula Batta; Pál Herczegh; Anikó Borbás
Journal:  Pharmaceuticals (Basel)       Date:  2020-06-29
  3 in total

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