Literature DB >> 23148171

Challenges in β(3)-Adrenoceptor Agonist Drug Development.

Jonathan R S Arch.   

Abstract

Entities:  

Year:  2011        PMID： 23148171      PMCID： PMC3474627          DOI： 10.1177/2042018811398517

Source DB:  PubMed          Journal:  Ther Adv Endocrinol Metab        ISSN： 2042-0188            Impact factor:   3.565


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  55 in total

1.  Molecular characterization of the human beta 3-adrenergic receptor.

Authors:  L J Emorine; S Marullo; M M Briend-Sutren; G Patey; K Tate; C Delavier-Klutchko; A D Strosberg
Journal:  Science       Date:  1989-09-08       Impact factor: 47.728

2.  beta1-adrenergic receptors mediate beta3-adrenergic-independent effects of CGP 12177 in brown adipose tissue.

Authors:  A A Konkar; Y Zhai; J G Granneman
Journal:  Mol Pharmacol       Date:  2000-02       Impact factor: 4.436

3.  The distribution of brown adipose tissue in the human.

Authors:  J M Heaton
Journal:  J Anat       Date:  1972-05       Impact factor: 2.610

Review 4.  beta(3)-Adrenoceptor agonists: potential, pitfalls and progress.

Authors:  Jonathan R S Arch
Journal:  Eur J Pharmacol       Date:  2002-04-12       Impact factor: 4.432

5.  (-)-CGP 12177 causes cardiostimulation and binds to cardiac putative beta 4-adrenoceptors in both wild-type and beta 3-adrenoceptor knockout mice.

Authors:  A J Kaumann; F Preitner; D Sarsero; P Molenaar; J P Revelli; J P Giacobino
Journal:  Mol Pharmacol       Date:  1998-04       Impact factor: 4.436

6.  Cold-activated brown adipose tissue in healthy men.

Authors:  Wouter D van Marken Lichtenbelt; Joost W Vanhommerig; Nanda M Smulders; Jamie M A F L Drossaerts; Gerrit J Kemerink; Nicole D Bouvy; Patrick Schrauwen; G J Jaap Teule
Journal:  N Engl J Med       Date:  2009-04-09       Impact factor: 91.245

7.  Phenethanolamine derivatives with calorigenic and antidiabetic qualities.

Authors:  M K Meier; L Alig; M E Bürgi-Saville; M Müller
Journal:  Int J Obes       Date:  1984

8.  Thermogenesis and weight control.

Authors:  T T Yen; M M McKee; N B Stamm
Journal:  Int J Obes       Date:  1984

9.  Treatment of obesity with thermogenic beta-adrenoceptor agonists: studies on BRL 26830A in rodents.

Authors:  J R Arch; A T Ainsworth; R D Ellis; V Piercy; V E Thody; P L Thurlby; C Wilson; S Wilson; P Young
Journal:  Int J Obes       Date:  1984

10.  Role of beta3-adrenergic receptors in the action of a tumour lipid mobilizing factor.

Authors:  S T Russell; K Hirai; M J Tisdale
Journal:  Br J Cancer       Date:  2002-02-01       Impact factor: 7.640
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  55 in total

Review 1.  Adrenoceptors in white, brown, and brite adipocytes.

Authors:  Bronwyn A Evans; Jon Merlin; Tore Bengtsson; Dana S Hutchinson
Journal:  Br J Pharmacol       Date:  2019-04-07       Impact factor: 8.739

Review 2.  Adipocyte lipolysis: from molecular mechanisms of regulation to disease and therapeutics.

Authors:  Alexander Yang; Emilio P Mottillo
Journal:  Biochem J       Date:  2020-03-13       Impact factor: 3.857

3.  Activation of human brown adipose tissue by a β3-adrenergic receptor agonist.

Authors:  Aaron M Cypess; Lauren S Weiner; Carla Roberts-Toler; Elisa Franquet Elía; Skyler H Kessler; Peter A Kahn; Jeffrey English; Kelly Chatman; Sunia A Trauger; Alessandro Doria; Gerald M Kolodny
Journal:  Cell Metab       Date:  2015-01-06       Impact factor: 27.287

4.  Beneficial Metabolic Effects of Mirabegron In Vitro and in High-Fat Diet-Induced Obese Mice.

Authors:  Lei Hao; Sheyenne Scott; Mehrnaz Abbasi; Yujiao Zu; Md Shahjalal Hossain Khan; Yang Yang; Dayong Wu; Ling Zhao; Shu Wang
Journal:  J Pharmacol Exp Ther       Date:  2019-04-02       Impact factor: 4.030

Review 5.  Adrenergic regulation of cellular plasticity in brown, beige/brite and white adipose tissues.

Authors:  Vanesa D Ramseyer; James G Granneman
Journal:  Adipocyte       Date:  2016-02-18       Impact factor: 4.534

6.  Might β3-adrenergic receptor agonists be useful in disorders of glucose homeostasis?

Authors:  Jeffrey S Flier
Journal:  J Clin Invest       Date:  2020-05-01       Impact factor: 14.808

Review 7.  Opportunities and challenges in the therapeutic activation of human energy expenditure and thermogenesis to manage obesity.

Authors:  Kong Y Chen; Robert J Brychta; Zahraa Abdul Sater; Thomas M Cassimatis; Cheryl Cero; Laura A Fletcher; Nikita S Israni; James W Johnson; Hannah J Lea; Joyce D Linderman; Alana E O'Mara; Kenneth Y Zhu; Aaron M Cypess
Journal:  J Biol Chem       Date:  2019-12-30       Impact factor: 5.157

8.  Regulation of Human Adipose Tissue Activation, Gallbladder Size, and Bile Acid Metabolism by a β3-Adrenergic Receptor Agonist.

Authors:  Alison S Baskin; Joyce D Linderman; Robert J Brychta; Suzanne McGehee; Esti Anflick-Chames; Cheryl Cero; James W Johnson; Alana E O'Mara; Laura A Fletcher; Brooks P Leitner; Courtney J Duckworth; Shan Huang; Hongyi Cai; H Martin Garraffo; Corina M Millo; William Dieckmann; Vladimir Tolstikov; Emily Y Chen; Fei Gao; Niven R Narain; Michael A Kiebish; Peter J Walter; Peter Herscovitch; Kong Y Chen; Aaron M Cypess
Journal:  Diabetes       Date:  2018-07-06       Impact factor: 9.461

Review 9.  Convertible visceral fat as a therapeutic target to curb obesity.

Authors:  Antonio Giordano; Andrea Frontini; Saverio Cinti
Journal:  Nat Rev Drug Discov       Date:  2016-03-11       Impact factor: 84.694

10.  HDAC11 suppresses the thermogenic program of adipose tissue via BRD2.

Authors:  Rushita A Bagchi; Bradley S Ferguson; Matthew S Stratton; Tianjing Hu; Maria A Cavasin; Lei Sun; Ying-Hsi Lin; Dianxin Liu; Pilar Londono; Kunhua Song; Maria F Pino; Lauren M Sparks; Steven R Smith; Philipp E Scherer; Sheila Collins; Edward Seto; Timothy A McKinsey
Journal:  JCI Insight       Date:  2018-08-09
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