Literature DB >> 23143641

Over-diagnosis of laryngopharyngeal reflux as the cause of hoarseness.

James P Thomas1, Fermin M Zubiaur.   

Abstract

The objectives of this study were: (1) to determine the percentage of patients seen in a private laryngology clinic with voice-related disorders previously diagnosed with and treated for laryngopharyngeal reflux (LPR); (2) to determine how many of those patients are found to have disorders other than LPR as a cause for their voice disorder. A retrospective, chart-review analysis of new patients was conducted from January 2005 through December 2007 in a private laryngology clinic setting. Patients with a previous diagnosis of LPR as the cause of hoarseness, with or without anti-reflux treatment were included. Incomplete charts and patients with additional diagnoses besides LPR where excluded. Patient charts were analyzed in search of different variables including chief complaint, previous medications and final diagnosis among others. 784 consecutive charts were reviewed. Inclusion criteria were met in 105 charts. 82 % had no improvement or felt worse after previous anti-reflux treatment while 18 % had significant or mild improvement. However, all patients remained with some degree of hoarseness. Final diagnosis by the author was diverse though none of the patients had laryngopharyngeal reflux as a final diagnosis and none of them noted worsening of their voice after respective treatment. Only 6 % felt the same after treatment and 9 % could not be found for follow-up. LPR has become an over-diagnosed entity. With a thorough history, vocal capability testing and physical exam, an accurate diagnosis for hoarseness can be made in the vast majority of cases. LPR may not be the cause of voice disorders and should not be assigned as a de facto diagnosis just because the cause of hoarseness is not readily identifiable.

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Year:  2012        PMID: 23143641     DOI: 10.1007/s00405-012-2244-8

Source DB:  PubMed          Journal:  Eur Arch Otorhinolaryngol        ISSN: 0937-4477            Impact factor:   2.503


  11 in total

1.  Prevalence of reflux in 113 consecutive patients with laryngeal and voice disorders.

Authors:  J A Koufman; M R Amin; M Panetti
Journal:  Otolaryngol Head Neck Surg       Date:  2000-10       Impact factor: 3.497

Review 2.  Meta-analysis of upper probe measurements in normal subjects and patients with laryngopharyngeal reflux.

Authors:  Albert L Merati; Hyun J Lim; Seckin O Ulualp; Robert J Toohill
Journal:  Ann Otol Rhinol Laryngol       Date:  2005-03       Impact factor: 1.547

Review 3.  Acid reflux treatment for hoarseness.

Authors:  C Hopkins; U Yousaf; M Pedersen
Journal:  Cochrane Database Syst Rev       Date:  2006-01-25

Review 4.  Prevalence of gastroesophagopharyngeal acid reflux events: an evidence-based systematic review.

Authors:  Seckin O Ulualp; Peter S Roland; Robert J Toohill; Reza Shaker
Journal:  Am J Otolaryngol       Date:  2005 Jul-Aug       Impact factor: 1.808

5.  Contact ulcer of the larynx.

Authors:  J Cherry; S I Margulies
Journal:  Laryngoscope       Date:  1968-11       Impact factor: 3.325

6.  The validity and reliability of the reflux finding score (RFS).

Authors:  P C Belafsky; G N Postma; J A Koufman
Journal:  Laryngoscope       Date:  2001-08       Impact factor: 3.325

Review 7.  Reflux and laryngitis: a systematic review.

Authors:  Sander Joniau; Anthony Bradshaw; Adrian Esterman; A Simon Carney
Journal:  Otolaryngol Head Neck Surg       Date:  2007-05       Impact factor: 3.497

Review 8.  Review article: the role of pH monitoring in extraoesophageal gastro-oesophageal reflux disease.

Authors:  M F Vaezi
Journal:  Aliment Pharmacol Ther       Date:  2006-03       Impact factor: 8.171

Review 9.  The otolaryngologic manifestations of gastroesophageal reflux disease (GERD): a clinical investigation of 225 patients using ambulatory 24-hour pH monitoring and an experimental investigation of the role of acid and pepsin in the development of laryngeal injury.

Authors:  J A Koufman
Journal:  Laryngoscope       Date:  1991-04       Impact factor: 3.325

10.  Validity and reliability of the reflux symptom index (RSI).

Authors:  Peter C Belafsky; Gregory N Postma; James A Koufman
Journal:  J Voice       Date:  2002-06       Impact factor: 2.009

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  5 in total

1.  Resource utilization and variation among practitioners for evaluating voice hoarseness secondary to suspected reflux disease: A retrospective chart review.

Authors:  Sydney R A Korsunsky; Leonel Camejo; Diep Nguyen; Rahul Mhaskar; Khattiya Chharath; Joy Gaziano; Joel Richter; Vic Velanovich
Journal:  Medicine (Baltimore)       Date:  2022-10-14       Impact factor: 1.817

Review 2.  The role of caffeine in otorhinolaryngology: guilty as charged?

Authors:  A Trinidade; T Robinson; J S Phillips
Journal:  Eur Arch Otorhinolaryngol       Date:  2013-08-11       Impact factor: 2.503

Review 3.  Laryngopharyngeal Reflux: A State-of-the-Art Algorithm Management for Primary Care Physicians.

Authors:  Jerome R Lechien; Sven Saussez; Vinciane Muls; Maria R Barillari; Carlos M Chiesa-Estomba; Stéphane Hans; Petros D Karkos
Journal:  J Clin Med       Date:  2020-11-10       Impact factor: 4.241

4.  Do Otolaryngologists Over- or Underestimate Laryngopharyngeal Reflux Symptoms and Findings in Clinical Practice? A Comparison Study between the True Prevalence and the Otolaryngologist-Estimated Prevalence of Symptoms and Findings.

Authors:  Jerome R Lechien
Journal:  J Clin Med       Date:  2022-09-01       Impact factor: 4.964

5.  Laryngopharyngeal reflux concept: what is known and what should we focus on?

Authors:  Seher Sirin; Ferhan Öz
Journal:  Braz J Otorhinolaryngol       Date:  2019-01-19
  5 in total

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