OBJECTIVE: The aim of this study was to estimate the efficacy of flexible spectral imaging color enhancement (FICE) on the detection of small intestinal diseases by capsule endoscopy (CE). METHODS: Six individuals without significant lesions and 18 patients with following diseases were selected: four tumors, five angioectasias, seven ulcerative diseases, one ulcerative lesion and tumor and one ulcerative lesion and angioectasia. Three endoscopists reviewed all CE videos on standard and three types of FICE modes and compared their sensitivity and specificity for detection of small intestinal diseases. RESULTS: The overall sensitivity of CE was 94.4% at standard mode, 90.7% at FICE channel (Ch) 1, 87.0% at FICE Ch 2 and 87.0% at FICE Ch 3 and the overall specificity of CE was 66.7%, 55.6%, 77.8% and 66.7%, respectively, per patient. There was no significant difference between the standard and each FICE mode. In per-lesion analysis, FICE Ch 1 detected more angioectasias and ulcerative lesions than the standard mode (angioectasia, 25.7 vs 21.0, P = 0.005; ulcerative lesions, 19.3 vs 14.0, P = 0.06). However, FICE Ch 1 missed more tumors than the standard mode (4.3 vs 10.0, P = 0.003). CONCLUSIONS: Although FICE Ch 1 is better in detecting angioectasias and ulcerative lesions and worse in tumors or polyps than the standard mode, the patient-based sensitivity and specificity of small intestinal diseases are not different between standard and each FICE mode. Further experiences with and improvement of FICE are required.
OBJECTIVE: The aim of this study was to estimate the efficacy of flexible spectral imaging color enhancement (FICE) on the detection of small intestinal diseases by capsule endoscopy (CE). METHODS: Six individuals without significant lesions and 18 patients with following diseases were selected: four tumors, five angioectasias, seven ulcerative diseases, one ulcerative lesion and tumor and one ulcerative lesion and angioectasia. Three endoscopists reviewed all CE videos on standard and three types of FICE modes and compared their sensitivity and specificity for detection of small intestinal diseases. RESULTS: The overall sensitivity of CE was 94.4% at standard mode, 90.7% at FICE channel (Ch) 1, 87.0% at FICE Ch 2 and 87.0% at FICE Ch 3 and the overall specificity of CE was 66.7%, 55.6%, 77.8% and 66.7%, respectively, per patient. There was no significant difference between the standard and each FICE mode. In per-lesion analysis, FICE Ch 1 detected more angioectasias and ulcerative lesions than the standard mode (angioectasia, 25.7 vs 21.0, P = 0.005; ulcerative lesions, 19.3 vs 14.0, P = 0.06). However, FICE Ch 1 missed more tumors than the standard mode (4.3 vs 10.0, P = 0.003). CONCLUSIONS: Although FICE Ch 1 is better in detecting angioectasias and ulcerative lesions and worse in tumors or polyps than the standard mode, the patient-based sensitivity and specificity of small intestinal diseases are not different between standard and each FICE mode. Further experiences with and improvement of FICE are required.
Authors: Cristiano Spada; Deirdre McNamara; Edward J Despott; Samuel Adler; Brooks D Cash; Ignacio Fernández-Urién; Hrvoje Ivekovic; Martin Keuchel; Mark McAlindon; Jean-Christophe Saurin; Simon Panter; Cristina Bellisario; Silvia Minozzi; Carlo Senore; Cathy Bennett; Michael Bretthauer; Mario Dinis-Ribeiro; Dirk Domagk; Cesare Hassan; Michal F Kaminski; Colin J Rees; Roland Valori; Raf Bisschops; Matthew D Rutter Journal: United European Gastroenterol J Date: 2019-05-15 Impact factor: 4.623
Authors: Tiago Cúrdia Gonçalves; Joana Magalhães; Pedro Boal Carvalho; Maria João Moreira; Bruno Rosa; José Cotter Journal: Diagn Ther Endosc Date: 2014-03-17
Authors: Mihai Rimbaş; Denise Carmen Mihaela Zahiu; Andrei Mihai Voiosu; Theodor Alexandru Voiosu; Alina Ana-Maria Zlate; Roxana Dinu; Domenico Galasso; Leonardo Minelli Grazioli; Mariachiara Campanale; Federico Barbaro; Bogdan Radu Mateescu; Bogdan Busuioc; Tiberiu Iordache; Oana Dolofan; Adelina Maria Popescu; Vasile Daniel Balaban; Mircea Mihai Raducan; Cristiano Spada; Cristian Răsvan Băicuş; Guido Costamagna Journal: Endosc Int Open Date: 2016-05-12