Literature DB >> 23133090

Role of gastric bypass in patients with unresectable advanced carcinoma of stomach.

Nagarjuna V Maturu1, Dinker R Pai, Vishnu N R Prasad.   

Abstract

CONTEXT: Role of bypass as a palliative surgery for advanced gastric cancer remains controversial. AIMS: To determine the role of bypass in advanced gastric cancer in comparision to resection as gold standard.
DESIGN: Hospital-based retrospective outcome as study.
METHODS: Patients were divided into three groups: group I (gastric resection), group II (bypass) and group III (exploratory laparotomy alone). The three groups were analysed for palliation of symptoms, operative morbidity and mortality and survival. STATISTICAL ANALYSIS USED: Chi-square, Fischer, One-way Anova, Unpaired-t, Kaplan-Meier analysis.
RESULTS: In-hospital morbidity was 19.38% (19 patients) for the entire study group. Bypass group had a lower morbidity rate as compared to the resection group (p=0.029). In-hospital mortality rate was 6.12% (6 patients) for the entire study group. Mortality rates did not differ between the groups. Patient satisfaction with palliation of symptoms was similar between gastric bypass and resection. Gastric resection group had significantly better survival (p=0.002) compared to the nonresective procedures. However, gastric bypass did not confer any survival benefit over exploratory laparotomy (p=0.501).
CONCLUSIONS: Gastric bypass can be done when resection is not possible as it palliates symptoms on par with resection and is associated with low operative morbidity though it does not improve the survival outlook of patients.

Entities:  

Keywords:  Cancer; Palliation; Stomach

Year:  2008        PMID: 23133090      PMCID: PMC3452365          DOI: 10.1007/s12262-008-0089-6

Source DB:  PubMed          Journal:  Indian J Surg        ISSN: 0973-9793            Impact factor:   0.656


  10 in total

1.  Does gastrojejunostomy for unresectable cancer of the gastric antrum offer satisfactory palliation?

Authors:  S Kikuchi; O Tsutsumi; N Kobayashi; H Tsukamoto; H Shimao; Y Sakakibara; Y Hiki; A Kakita
Journal:  Hepatogastroenterology       Date:  1999 Jan-Feb

2.  Does the surgical stress associated with palliative resection for patients with incurable gastric cancer with distant metastasis shorten their survival?

Authors:  Yoshihiro Moriwaki; Chikara Kunisaki; Syunsuke Kobayashi; Hirofumi Harada; Shinsuke Imai; Chitaka Kasaoka
Journal:  Hepatogastroenterology       Date:  2004 May-Jun

3.  Indications and use of palliative surgery-results of Society of Surgical Oncology survey.

Authors:  Laurence E McCahill; Robert Krouse; David Chu; Gloria Juarez; Gwen C Uman; Betty Ferrell; Lawrence D Wagman
Journal:  Ann Surg Oncol       Date:  2002 Jan-Feb       Impact factor: 5.344

4.  Risk factors for complications following resection of large gastric cancer.

Authors:  K Yasuda; N Shiraishi; Y Adachi; M Inomata; K Sato; S Kitano
Journal:  Br J Surg       Date:  2001-06       Impact factor: 6.939

5.  Palliative surgery for far-advanced gastric cancer: a retrospective study on 305 consecutive patients.

Authors:  G B Doglietto; F Pacelli; P Caprino; S Alfieri; C Carriero; M Malerba; F Crucitti
Journal:  Am Surg       Date:  1999-04       Impact factor: 0.688

6.  Palliative gastrojejunostomy for advanced carcinoma of the stomach.

Authors:  N N Lo; S G Kee; R Nambiar
Journal:  Ann Acad Med Singapore       Date:  1991-05       Impact factor: 2.473

7.  Prognostic significance of alarm symptoms in patients with gastric cancer.

Authors:  M R Stephens; W G Lewis; S White; G R J C Blackshaw; P Edwards; J D Barry; M C Allison
Journal:  Br J Surg       Date:  2005-07       Impact factor: 6.939

8.  A prospective, symptom related, outcomes analysis of 1022 palliative procedures for advanced cancer.

Authors:  Thomas J Miner; Murray F Brennan; David P Jaques
Journal:  Ann Surg       Date:  2004-10       Impact factor: 12.969

9.  [Morbidity and mortality related to gastroenteroanastomosis in advanced gastric cancer].

Authors:  F Berrospi; E Ruiz; C Morante; J Celis; J A Montalbelti
Journal:  Rev Gastroenterol Peru       Date:  1995 Jan-Apr

10.  Surgery for stage IV gastric cancer.

Authors:  Heriberto Medina-Franco; Alan Contreras-Saldívar; Antonio Ramos-De La Medina; Pedro Palacios-Sanchez; Rubén Cortés-González; Javier Alvarez-Tostado Ugarte
Journal:  Am J Surg       Date:  2004-04       Impact factor: 2.565

  10 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.