Literature DB >> 23129324

Tracking the bioreduction of disulfide-containing cationic dendrimers.

Lorine Brülisauer1, Nadia Kathriner, Mark Prenrecaj, Marc A Gauthier, Jean-Christophe Leroux.   

Abstract

Disulfides enhance the transfection efficacy and reduce the toxicity of cationic gene delivery polymers. A quantitative analysis is provided of the bioreduction of a dynamic bioreducible dendritic polycationic probe in four cell lines. Such knowledge is indispensible for understanding and optimizing bioreducible drug and gene delivery systems.
Copyright © 2012 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

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Year:  2012        PMID： 23129324     DOI： 10.1002/anie.201207070

Source DB:  PubMed          Journal:  Angew Chem Int Ed Engl        ISSN： 1433-7851            Impact factor:   15.336


  10 in total

1.  Cancer cell surface induced peptide folding allows intracellular translocation of drug.

Authors:  Scott H Medina; Joel P Schneider
Journal:  J Control Release       Date:  2015-05-13       Impact factor: 9.776

Review 2.  Bioreducible polycations in nucleic acid delivery: past, present, and future trends.

Authors:  David Oupický; Jing Li
Journal:  Macromol Biosci       Date:  2014-03-28       Impact factor: 4.979

Review 3.  Bioreducible polycations as shuttles for therapeutic nucleic acid and protein transfection.

Authors:  Philipp M Klein; Ernst Wagner
Journal:  Antioxid Redox Signal       Date:  2014-01-08       Impact factor: 8.401

4.  The self-assembling camptothecin-tocopherol prodrug: An effective approach for formulating camptothecin.

Authors:  Jianqin Lu; Chuang Liu; Pengcheng Wang; Mohammed Ghazwani; Jieni Xu; Yixian Huang; Xiaochao Ma; Peijun Zhang; Song Li
Journal:  Biomaterials       Date:  2015-05-31       Impact factor: 12.479

5.  Self-immolative polycations as gene delivery vectors and prodrugs targeting polyamine metabolism in cancer.

Authors:  Yu Zhu; Jing Li; Shrey Kanvinde; Zhiyi Lin; Stuart Hazeldine; Rakesh K Singh; David Oupický
Journal:  Mol Pharm       Date:  2014-08-25       Impact factor: 4.939

6.  Diselenolane-mediated cellular uptake.

Authors:  Nicolas Chuard; Amalia I Poblador-Bahamonde; Lili Zong; Eline Bartolami; Jana Hildebrandt; Wolfgang Weigand; Naomi Sakai; Stefan Matile
Journal:  Chem Sci       Date:  2018-01-17       Impact factor: 9.825

7.  Epidithiodiketopiperazines: Strain-Promoted Thiol-Mediated Cellular Uptake at the Highest Tension.

Authors:  Lili Zong; Eline Bartolami; Daniel Abegg; Alexander Adibekian; Naomi Sakai; Stefan Matile
Journal:  ACS Cent Sci       Date:  2017-04-06       Impact factor: 14.553

8.  Cell-Penetrating Streptavidin: A General Tool for Bifunctional Delivery with Spatiotemporal Control, Mediated by Transport Systems Such as Adaptive Benzopolysulfane Networks.

Authors:  Javier López-Andarias; Jacques Saarbach; Dimitri Moreau; Yangyang Cheng; Emmanuel Derivery; Quentin Laurent; Marcos González-Gaitán; Nicolas Winssinger; Naomi Sakai; Stefan Matile
Journal:  J Am Chem Soc       Date:  2020-02-28       Impact factor: 15.419

9.  How Divalent Cations Interact with the Internal Channel Site of Guanine Quadruplexes.

Authors:  Francesco Zaccaria; Stephanie C C van der Lubbe; Celine Nieuwland; Trevor A Hamlin; Célia Fonseca Guerra
Journal:  Chemphyschem       Date:  2021-09-23       Impact factor: 3.520

10.  Presumed LRP1-targeting transport peptide delivers β-secretase inhibitor to neurons in vitro with limited efficiency.

Authors:  Jong Ah Kim; Tommaso Casalini; Davide Brambilla; Jean-Christophe Leroux
Journal:  Sci Rep       Date:  2016-09-29       Impact factor: 4.379
  10 in total

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