BACKGROUND AND PURPOSE: The shorter the time interval between the estimation of the ischemic core by imaging and reperfusion, the more likely that core expansion is minimized. We aimed to assess the feasibility of achieving an ultrashort imaging to reperfusion time in routine clinical practice. METHODS: The study subjects were a prospective cohort of patients with acute ischemic stroke treated with endovascular therapy in a tertiary center in whom an imaging to reperfusion time of <60 min was achieved. RESULTS: Imaging to reperfusion time of <60 min was accomplished in 11 patients. The median baseline National Institutes of Health Stroke Scale (NIHSS) score was 11 and the median baseline Alberta Stroke Program Early CT Score (ASPECTS) was 8. The median time interval from imaging to endovascular reperfusion was 47 min. The median ASPECTS score on the 24 h CT scan was also 8 and the median 24 h NIHSS score was 1. Upon discharge, 82% of patients achieved a modified Rankin scale score of ≤ 1. CONCLUSIONS: An imaging to endovascular reperfusion time of <60 min is feasible and resulted in minimal core expansion on follow-up imaging in patients with acute ischemic stroke.
BACKGROUND AND PURPOSE: The shorter the time interval between the estimation of the ischemic core by imaging and reperfusion, the more likely that core expansion is minimized. We aimed to assess the feasibility of achieving an ultrashort imaging to reperfusion time in routine clinical practice. METHODS: The study subjects were a prospective cohort of patients with acute ischemic stroke treated with endovascular therapy in a tertiary center in whom an imaging to reperfusion time of <60 min was achieved. RESULTS: Imaging to reperfusion time of <60 min was accomplished in 11 patients. The median baseline National Institutes of Health Stroke Scale (NIHSS) score was 11 and the median baseline Alberta Stroke Program Early CT Score (ASPECTS) was 8. The median time interval from imaging to endovascular reperfusion was 47 min. The median ASPECTS score on the 24 h CT scan was also 8 and the median 24 h NIHSS score was 1. Upon discharge, 82% of patients achieved a modified Rankin scale score of ≤ 1. CONCLUSIONS: An imaging to endovascular reperfusion time of <60 min is feasible and resulted in minimal core expansion on follow-up imaging in patients with acute ischemic stroke.
Authors: Mohammed A Almekhlafi; Sachin Mishra; Jamsheed A Desai; Vivek Nambiar; Ondrej Volny; Ankur Goel; Muneer Eesa; Andrew M Demchuk; Bijoy K Menon; Mayank Goyal Journal: Interv Neuroradiol Date: 2014-02-10 Impact factor: 1.610
Authors: Mayank Goyal; Mohammed A Almekhlafi; Liqiong Fan; Bijoy K Menon; Andrew M Demchuk; Sharon D Yeatts; Michael D Hill; Thomas Tomsick; Pooja Khatri; Osama O Zaidat; Edward C Jauch; Muneer Eesa; Tudor G Jovin; Joseph P Broderick Journal: Circulation Date: 2014-05-09 Impact factor: 29.690
Authors: Jeffrey L Saver; Tudor G Jovin; Wade S Smith; Gregory W Albers; Jean-Claude Baron; Johannes Boltze; Joseph P Broderick; Lisa A Davis; Andrew M Demchuk; Salvatore DeSena; Jens Fiehler; Philip B Gorelick; Werner Hacke; Bill Holt; Reza Jahan; Hui Jing; Pooja Khatri; Chelsea S Kidwell; Kennedy R Lees; Michael H Lev; David S Liebeskind; Marie Luby; Patrick Lyden; J Thomas Megerian; J Mocco; Keith W Muir; Howard A Rowley; Richard M Ruedy; Sean I Savitz; Vitas J Sipelis; Samuel K Shimp; Lawrence R Wechsler; Max Wintermark; Ona Wu; Dileep R Yavagal; Albert J Yoo Journal: Stroke Date: 2013-11-05 Impact factor: 7.914
Authors: Tim W Malisch; Osama O Zaidat; Alicia C Castonguay; Franklin A Marden; Rishi Gupta; Chung-Huan J Sun; Coleman O Martin; William E Holloway; Nils Mueller-Kronast; Joey English; Italo Linfante; Guilherme Dabus; Hormozd Bozorgchami; Andrew Xavier; Ansaar T Rai; Michael Froehler; Aamir Badruddin; Thanh N Nguyen; M Asif Taqi; Michael G Abraham; Vallabh Janardhan; Hashem Shaltoni; Robin Novakovic; Albert J Yoo; Alex Abou-Chebl; Peng Roc Chen; Gavin W Britz; Ritesh Kaushal; Ashish Nanda; Raul G Nogueira Journal: Interv Neurol Date: 2017-10-11