Warning: Undefined array key "mm" in /www/wwwroot/www.ai-bt.com/si.php on line 10 Deprecated: trim(): Passing null to parameter #1 ($string) of type string is deprecated in /www/wwwroot/www.ai-bt.com/si.php on line 10 Metabolic plasticity in stem cell homeostasis and differentiation.

Literature DB >> 23122287

Metabolic plasticity in stem cell homeostasis and differentiation.

Clifford D L Folmes¹, Petras P Dzeja, Timothy J Nelson, Andre Terzic.

Abstract

Plasticity in energy metabolism allows stem cells to match the divergent demands of self-renewal and lineage specification. Beyond a role in energetic support, new evidence implicates nutrient-responsive metabolites as mediators of crosstalk between metabolic flux, cellular signaling, and epigenetic regulation of cell fate. Stem cell metabolism also offers a potential target for controlling tissue homeostasis and regeneration in aging and disease. In this Perspective, we cover recent progress establishing an emerging relationship between stem cell metabolism and cell fate control.

Entities: Chemical Disease Gene Species

Mesh：

Year: 2012 PMID： 23122287 PMCID： PMC3593051 DOI： 10.1016/j.stem.2012.10.002

Source DB: PubMed Journal: Cell Stem Cell ISSN： 1875-9777 Impact factor: 24.633

100 in total

Review 1. Linking functional decline of telomeres, mitochondria and stem cells during ageing.

Authors: Ergün Sahin; Ronald A Depinho
Journal: Nature Date: 2010-03-25 Impact factor: 49.962

2. Mitochondrial transfer between cells can rescue aerobic respiration.

Authors: Jeffrey L Spees; Scott D Olson; Mandolin J Whitney; Darwin J Prockop
Journal: Proc Natl Acad Sci U S A Date: 2006-01-23 Impact factor: 11.205

Review 3. Stem cell states, fates, and the rules of attraction.

Authors: Tariq Enver; Martin Pera; Carsten Peterson; Peter W Andrews
Journal: Cell Stem Cell Date: 2009-05-08 Impact factor: 24.633

4. Oct1 loss of function induces a coordinate metabolic shift that opposes tumorigenicity.

Authors: Arvind Shakya; Robert Cooksey; James E Cox; Victoria Wang; Donald A McClain; Dean Tantin
Journal: Nat Cell Biol Date: 2009-02-15 Impact factor: 28.824

5. Reversal of a mitochondrial DNA defect in human skeletal muscle.

Authors: K M Clark; L A Bindoff; R N Lightowlers; R M Andrews; P G Griffiths; M A Johnson; E J Brierley; D M Turnbull
Journal: Nat Genet Date: 1997-07 Impact factor: 38.330

6. The Lkb1 metabolic sensor maintains haematopoietic stem cell survival.

Authors: Sushma Gurumurthy; Stephanie Z Xie; Brinda Alagesan; Judith Kim; Rushdia Z Yusuf; Borja Saez; Alexandros Tzatsos; Fatih Ozsolak; Patrice Milos; Francesco Ferrari; Peter J Park; Orian S Shirihai; David T Scadden; Nabeel Bardeesy
Journal: Nature Date: 2010-12-02 Impact factor: 49.962

7. Mitochondrial function controls proliferation and early differentiation potential of embryonic stem cells.

Authors: Sudip Mandal; Anne G Lindgren; Anand S Srivastava; Amander T Clark; Utpal Banerjee
Journal: Stem Cells Date: 2011-03 Impact factor: 6.277

8. Mitochondrial DNA replication during differentiation of murine embryonic stem cells.

Authors: Joao M Facucho-Oliveira; Jon Alderson; Emma C Spikings; Stuart Egginton; Justin C St John
Journal: J Cell Sci Date: 2007-10-30 Impact factor: 5.285

9. Glycolytic network restructuring integral to the energetics of embryonic stem cell cardiac differentiation.

Authors: Susan Chung; D Kent Arrell; Randolph S Faustino; Andre Terzic; Petras P Dzeja
Journal: J Mol Cell Cardiol Date: 2010-01-04 Impact factor: 5.000

10. Carbon metabolism-mediated myogenic differentiation.

Authors: Abigail L Bracha; Arvind Ramanathan; Sui Huang; Donald E Ingber; Stuart L Schreiber
Journal: Nat Chem Biol Date: 2010-01-17 Impact factor: 15.040

256 in total

1. Metabolic exit from naive pluripotency.

Authors: Jun Wu; Juan Carlos Izpisua Belmonte
Journal: Nat Cell Biol Date: 2015-12 Impact factor: 28.824

2. A Simple Method for Labeling Human Embryonic Stem Cells Destined to Lose Undifferentiated Potency.

Authors: Ayako Kumagai; Mika Suga; Kana Yanagihara; Yumi Itoh; Hiroshi Takemori; Miho K Furue
Journal: Stem Cells Transl Med Date: 2016-01-27 Impact factor: 6.940

3. Natural underlying mtDNA heteroplasmy as a potential source of intra-person hiPSC variability.

Authors: Ester Perales-Clemente; Alexandra N Cook; Jared M Evans; Samantha Roellinger; Frank Secreto; Valentina Emmanuele; Devin Oglesbee; Vamsi K Mootha; Michio Hirano; Eric A Schon; Andre Terzic; Timothy J Nelson
Journal: EMBO J Date: 2016-07-19 Impact factor: 11.598

4. Density-Dependent Metabolic Heterogeneity in Human Mesenchymal Stem Cells.

Authors: Yijun Liu; Nathalie Muñoz; Bruce A Bunnell; Timothy M Logan; Teng Ma
Journal: Stem Cells Date: 2015-08-14 Impact factor: 6.277

Review 5. Energy metabolism in the acquisition and maintenance of stemness.

Authors: Clifford D L Folmes; Andre Terzic
Journal: Semin Cell Dev Biol Date: 2016-02-08 Impact factor: 7.727

Review 6. Eat, breathe, ROS: controlling stem cell fate through metabolism.

Authors: Dieter A Kubli; Mark A Sussman
Journal: Expert Rev Cardiovasc Ther Date: 2017-04-21

7. Gerometabolites: the pseudohypoxic aging side of cancer oncometabolites.

Authors: Javier A Menendez; Tomás Alarcón; Jorge Joven
Journal: Cell Cycle Date: 2014-02-03 Impact factor: 4.534

8. Specific ablation of Nampt in adult neural stem cells recapitulates their functional defects during aging.

Authors: Liana R Stein; Shin-ichiro Imai
Journal: EMBO J Date: 2014-05-08 Impact factor: 11.598

9. Metabolic control of primed human pluripotent stem cell fate and function by the miR-200c-SIRT2 axis.

Authors: Young Cha; Min-Joon Han; Hyuk-Jin Cha; Janet Zoldan; Alison Burkart; Jin Hyuk Jung; Yongwoo Jang; Chun-Hyung Kim; Ho-Chang Jeong; Byung-Gyu Kim; Robert Langer; C Ronald Kahn; Leonard Guarente; Kwang-Soo Kim
Journal: Nat Cell Biol Date: 2017-04-24 Impact factor: 28.824

Review 10. Mitochondria in pluripotent stem cells: stemness regulators and disease targets.

Authors: Clifford Dl Folmes; Hong Ma; Shoukhrat Mitalipov; Andre Terzic
Journal: Curr Opin Genet Dev Date: 2016-03-05 Impact factor: 5.578