Literature DB >> 23119656

Management of acute vertigo with betahistine.

R A Bradoo1, N K Nerurkar, J B Mhapankar, S F Patil, D G Kute.   

Abstract

This open, prospective study was carried out in 29 outpatients of vertigo with Betahistine treatment at a dose of 16 mg three times daily far a maximum treatment period of 6 weeks or earlier until remission of vertigo attacks. The evaluations were carried out based on three parameters such as frequency, duration, and severity of vertigo attacks. Betahistino showed a significant improvement in the three parameters of frequency, duration and severity of vertigo attacks. Associated symptoms such as tinnitus, nausea, vomiting, headache, faintness showed a significant improvement with the therapy. Subgroup analysis showed a significant improvement of patients with severe and incapacitating verlign attaeks at baseline. Thus, this study proves excellent efficacy and goad tolerability of Betahistine as an anti-vertigo drug at a dose of 16 mg three times daily and gives a new insight for controlling acute or severe vertigo attacks without causing sedation.

Entities:  

Year:  2000        PMID: 23119656      PMCID: PMC3451274          DOI: 10.1007/BF03000335

Source DB:  PubMed          Journal:  Indian J Otolaryngol Head Neck Surg        ISSN: 2231-3796


  9 in total

1.  Rote of adaptation exercises in clinical practice.

Authors:  M V Kirtane
Journal:  Indian J Otolaryngol Head Neck Surg       Date:  1999-04

2.  Cochlear blood flow in response to vasodilating drugs and some related agents.

Authors:  F Suga; J B Snow
Journal:  Laryngoscope       Date:  1969-11       Impact factor: 3.325

3.  Vertigo. Current concepts in management.

Authors:  W J Oosterveld
Journal:  Drugs       Date:  1985-09       Impact factor: 9.546

4.  Betahistine in peripheral vertigo: a double-blind, placebo-controlled, cross-over study of Serc versus placebo.

Authors:  P Canty; J Valentine
Journal:  J Laryngol Otol       Date:  1981-07       Impact factor: 1.469

5.  Vertebrobasilar arterial insufficiency with dementia. Controlled trials of treatment with betahistine hydrochloride.

Authors:  V M Rivera; J S Meyer; P E Baer; G M Faibish; N T Mathew; A Hartmann
Journal:  J Am Geriatr Soc       Date:  1974-09       Impact factor: 5.562

6.  Inhibitory effect of betahistine on polysynaptic neurons in the lateral vestibular nucleus.

Authors:  H Unemoto; M Sasa; S Takaori; J Ito; I Matsuoka
Journal:  Arch Otorhinolaryngol       Date:  1982

7.  Betahistine dihydrochloride treatment facilitates vestibular compensation in the cat.

Authors:  B Tighilet; J Leonard; M Lacour
Journal:  J Vestib Res       Date:  1995 Jan-Feb       Impact factor: 2.435

8.  Effect of betahistine dihydrochloride on induced vestibular nystagmus: a double blind study.

Authors:  W J Oosterveld
Journal:  Clin Otolaryngol Allied Sci       Date:  1987-04

9.  Actions of betahistine at histamine receptors in the brain.

Authors:  J M Arrang; M Garbarg; T T Quach; E Yeramian; J C Schwartz
Journal:  Eur J Pharmacol       Date:  1985-04-23       Impact factor: 4.432

  9 in total
  1 in total

1.  A practical cochlear implant for India.

Authors:  William F House; Khandhar Vinod
Journal:  Indian J Otolaryngol Head Neck Surg       Date:  2003-03
  1 in total

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