Literature DB >> 23118449

Complete genome sequence of the novel Escherichia coli phage phAPEC8.

J Tsonos1, E M Adriaenssens, J Klumpp, J-P Hernalsteens, R Lavigne, H De Greve.   

Abstract

Bacteriophage phAPEC8 is an Escherichia coli-infecting myovirus, isolated on an avian pathogenic Escherichia coli (APEC) strain. APEC strains cause colibacillosis in poultry, resulting in high mortality levels and important economic losses. Genomic analysis of the 147,737-bp double-stranded DNA phAPEC8 genome revealed that 53% of the 269 encoded proteins are unique to this phage. Its closest relatives include the Salmonella phage PVP-SE1 and the coliphage rv5, with 19% and 18% similar proteins, respectively. As such, phAPEC8 represents a novel, phylogenetically distinct clade within the Myoviridae, with molecular properties suitable for phage therapy applications.

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Year:  2012        PMID： 23118449      PMCID： PMC3497662          DOI： 10.1128/JVI.02374-12

Source DB:  PubMed          Journal:  J Virol        ISSN： 0022-538X            Impact factor:   5.103


  15 in total

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Review 4.  Ten years of bacterial genome sequencing: comparative-genomics-based discoveries.

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3.  Complete Genome Sequences of Two Escherichia coli Phages, vB_EcoM_ ESCO5 and vB_EcoM_ESCO13, Which Are Related to phAPEC8.

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6.  The host-range, genomics and proteomics of Escherichia coli O157:H7 bacteriophage rV5.

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  10 in total

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