Literature DB >> 23107738

A new hydroxytyrosol metabolite identified in human plasma: hydroxytyrosol acetate sulphate.

Laura Rubió1, Alba Macià, Rosa M Valls, Anna Pedret, Maria-Paz Romero, Rosa Solà, Maria-José Motilva.   

Abstract

We report progress in the study of olive oil phenolic metabolites in humans and identify a new hydroxytyrosol metabolite called hydroxytyrosol acetate sulphate, which was determined using tandem MS, after ingestion of 30 ml of olive oil with a high phenolic content (500 mg/kg oil), reaching a maximum concentration of 1.63 μM. In order to understand and explain the generation of this metabolite, two different pathways are proposed.
Copyright © 2012 Elsevier Ltd. All rights reserved.

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Year:  2012        PMID： 23107738     DOI： 10.1016/j.foodchem.2012.02.192

Source DB:  PubMed          Journal:  Food Chem        ISSN： 0308-8146            Impact factor:   7.514


  7 in total

1.  Gender differences in plasma and urine metabolites from Sprague-Dawley rats after oral administration of normal and high doses of hydroxytyrosol, hydroxytyrosol acetate, and DOPAC.

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Journal:  Eur J Nutr       Date:  2015-10-13       Impact factor: 5.614

2.  Availability and Metabolic Fate of Olive Phenolic Alcohols Hydroxytyrosol and Tyrosol in the Human GI Tract Simulated by the In Vitro GIDM-Colon Model.

Authors:  Maria Eleni Sakavitsi; Annelies Breynaert; Theodora Nikou; Stef Lauwers; Luc Pieters; Nina Hermans; Maria Halabalaki
Journal:  Metabolites       Date:  2022-04-26

3.  Olive and grape seed extract prevents post-traumatic osteoarthritis damages and exhibits in vitro anti IL-1β activities before and after oral consumption.

Authors:  Elsa Mével; Christophe Merceron; Claire Vinatier; Stéphanie Krisa; Tristan Richard; Martial Masson; Julie Lesoeur; Vincent Hivernaud; Olivier Gauthier; Jérôme Abadie; Geoffroy Nourissat; Xavier Houard; Yohann Wittrant; Nelly Urban; Laurent Beck; Jérôme Guicheux
Journal:  Sci Rep       Date:  2016-09-19       Impact factor: 4.379

Review 4.  Phenolic Compounds Characteristic of the Mediterranean Diet in Mitigating Microglia-Mediated Neuroinflammation.

Authors:  Ruth Hornedo-Ortega; Ana B Cerezo; Rocío M de Pablos; Stéphanie Krisa; Tristan Richard; M Carmen García-Parrilla; Ana M Troncoso
Journal:  Front Cell Neurosci       Date:  2018-10-23       Impact factor: 5.505

Review 5.  Virgin Olive Oil and Health: Summary of the III International Conference on Virgin Olive Oil and Health Consensus Report, JAEN (Spain) 2018.

Authors:  José J Gaforio; Francesco Visioli; Catalina Alarcón-de-la-Lastra; Olga Castañer; Miguel Delgado-Rodríguez; Monserrat Fitó; Antonio F Hernández; Jesús R Huertas; Miguel A Martínez-González; Javier A Menendez; Jesús de la Osada; Angeliki Papadaki; Tesifón Parrón; Jorge E Pereira; María A Rosillo; Cristina Sánchez-Quesada; Lukas Schwingshackl; Estefanía Toledo; Aristidis M Tsatsakis
Journal:  Nutrients       Date:  2019-09-01       Impact factor: 5.717

Review 6.  Application of Hydroxytyrosol in the Functional Foods Field: From Ingredient to Dietary Supplements.

Authors:  Andreia F R Silva; Daniela Resende; Mariana Monteiro; Manuel A Coimbra; Artur M S Silva; Susana M Cardoso
Journal:  Antioxidants (Basel)       Date:  2020-12-08

Review 7.  Polyphenols, the Healthy Brand of Olive Oil: Insights and Perspectives.

Authors:  Mauro Finicelli; Tiziana Squillaro; Umberto Galderisi; Gianfranco Peluso
Journal:  Nutrients       Date:  2021-10-27       Impact factor: 5.717
  7 in total

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