Literature DB >> 23105482

Effect of arogh-A polyherbal formulation on the marker enzymes in isoproterenol induced myocardial injury.

S Suchalatha1, C S Shyamala Devi.   

Abstract

To study the protective role of Arogh on isoproterenol induced myocardial damage in rats. The effect of Arogh pretreatment on isoproterenol induced myocardial damage was assessed by studying the levels of lipid peroxides and changes in the activity of marker enzymes such as creatine kinase, lactate dehydrogenase and transaminases in serum and heart tissue. In isoproterenol administered rats, a significant decrease was observed in the activity of marker enzymes in the heart with a corresponding increase in their levels in serum. Lipid peroxide levels increased significantly in the serum and heart. In rats pretreated with arogh, the level of lipid peroxides and the activity of marker enzymes were maintained at near normal values. Pretreatment with Arogh offered a protective effect against isoproterenol induced myocardial damage in rats as evidenced by LDH isoenzyme patterm and histopathological studies of heart tissue.

Entities:  

Keywords:  Arogh; isoproterenol; lipid peroxides; marker enzymes; myocardial infarction

Year:  2004        PMID： 23105482      PMCID： PMC3454197          DOI： 10.1007/BF02894283

Source DB:  PubMed          Journal:  Indian J Clin Biochem        ISSN： 0970-1915


  14 in total

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Journal:  Anal Biochem       Date:  1979-06       Impact factor: 3.365

5.  Creatine kinase and aspartate aminotransferase in experimental model to predict size of cardiac infarct.

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Journal:  Indian J Exp Biol       Date:  1988-03       Impact factor: 0.818

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Journal:  Indian J Exp Biol       Date:  1980-12       Impact factor: 0.818

8.  Effect of KRN2391, a novel vasodilator, on various experimental anginal models in rats.

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Journal:  Jpn J Pharmacol       Date:  1993-09

9.  Antioxidant actions of thymol, carvacrol, 6-gingerol, zingerone and hydroxytyrosol.

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Journal:  Food Chem Toxicol       Date:  1994-01       Impact factor: 6.023

10.  Anti-inflammatory and anti-nociceptive activity of disodium glycyrrhetinic acid hemiphthalate.

Authors:  G Khaksa; M E Zolfaghari; A R Dehpour; T Samadian
Journal:  Planta Med       Date:  1996-08       Impact factor: 3.352
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  6 in total

1.  Morin, a flavonoid, on lipid peroxidation and antioxidant status in experimental myocardial ischemic rats.

Authors:  Khalid S Al-Numair; Govindasamy Chandramohan; Mohammed A Alsaif; Chinnadurai Veeramani; Ahmed S El Newehy
Journal:  Afr J Tradit Complement Altern Med       Date:  2014-04-03

2.  Investigation of effects of Lacidipine, Ramipril and Valsartan on DNA damage and oxidative stress occurred in acute and chronic periods following isoproterenol-induced myocardial infarct in rats.

Authors:  Mevlut Sait Keles; Yasin Bayir; Halis Suleyman; Zekai Halici
Journal:  Mol Cell Biochem       Date:  2009-03-19       Impact factor: 3.396

3.  Hemidesmus indicus and Hibiscus rosa-sinensis Affect Ischemia Reperfusion Injury in Isolated Rat Hearts.

Authors:  Vinoth Kumar Megraj Khandelwal; R Balaraman; Dezider Pancza; Táňa Ravingerová
Journal:  Evid Based Complement Alternat Med       Date:  2010-09-07       Impact factor: 2.629

4.  Origanum majorana L. Extract Protects Against Isoproterenol-Induced Cardiotoxicity in Rats.

Authors:  Abeer M Rababa'h; Miya A Alzoubi
Journal:  Cardiovasc Toxicol       Date:  2021-03-30       Impact factor: 3.231

5.  Investigation into the optimal surgical conditions for coronary artery ligation for establishing a myocardial infarction model in mice.

Authors:  Xia Yue; Hongsheng Yu; Xialu Lin; Kui Liu; Xin Wang; Fei Zhou; Jinshun Zhao; Baobo Zou
Journal:  Exp Ther Med       Date:  2013-06-13       Impact factor: 2.447

6.  Evaluation of cardioprotective effect of silk cocoon (Abresham) on isoprenaline-induced myocardial infarction in rats.

Authors:  Ritesh Kumar Srivastav; Hefazat Hussain Siddiqui; Tarique Mahmood; Farogh Ahsan
Journal:  Avicenna J Phytomed       Date:  2013
  6 in total

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