| Literature DB >> 23105374 |
Abstract
Lipid peroxidation by measurement of Thiobarbituric Acid Reactive Substances (TBARS) and antioxidant status by determining the activities of the enzymes, Catalase (Cat), Glutathione Peroxidase (GPx) and Superoxide Dismutase (SOD) and the level of Reduced Glutathione (GSH) in the erythrocytes of patients with type 2 Diabetes Mellitus were investigated. It was observed that the level of TBARS in the erythrocytes was increased by 50% showing a significant generation of free radicals in the erythrocytes of these patients. The activities of both Cat and SOD were enhanced while that of GPx was not altered. The level of GSH was also not changed.Entities:
Keywords: Catalase; Glutathione; Peroxidase; Superoxide Dismutase; Type 2 Diabetes
Year: 2003 PMID: 23105374 PMCID: PMC3453734 DOI: 10.1007/BF02867668
Source DB: PubMed Journal: Indian J Clin Biochem ISSN: 0970-1915