Literature DB >> 23101139

Genomic medicine: challenges and opportunities for physicians.

H Burton1, T Cole, A M Lucassen.   

Abstract

Medicine has always striven to personalise or stratify approaches towards individual patients, but recently these terms have been applied particularly to denote improved disease sub-classification achieved through new genetic and genomic technologies. Techniques to analyse a person's genetic code have improved in sensitivity exponentially over recent years and at the same time the cost of such analyses has become affordable to routine NHS care. This article highlights the significant opportunities that genomics brings to healthcare, as well as some of the practical and ethical challenges.

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Year:  2012        PMID: 23101139      PMCID: PMC4953761          DOI: 10.7861/clinmedicine.12-5-416

Source DB:  PubMed          Journal:  Clin Med (Lond)        ISSN: 1470-2118            Impact factor:   2.659


  7 in total

1.  Compare and contrast: a cross-national study across UK, USA and Greek experts regarding return of incidental findings from clinical sequencing.

Authors:  Elli G Gourna; Natalie Armstrong; Susan E Wallace
Journal:  Eur J Hum Genet       Date:  2015-06-10       Impact factor: 4.246

2.  An inter-professional approach to personalized medicine education: one institution's experience.

Authors:  Christine M Formea; Wayne T Nicholson; Carolyn Rohrer Vitek
Journal:  Per Med       Date:  2015-03       Impact factor: 2.512

Review 3.  Human Leukocyte Antigen (HLA) System: Genetics and Association with Bacterial and Viral Infections.

Authors:  Sadeep Medhasi; Narisara Chantratita
Journal:  J Immunol Res       Date:  2022-05-26       Impact factor: 4.493

Review 4.  The role of the complement system in age-related macular degeneration.

Authors:  Bernhard H F Weber; Peter Charbel Issa; Diana Pauly; Philipp Herrmann; Felix Grassmann; Frank G Holz
Journal:  Dtsch Arztebl Int       Date:  2014-02-21       Impact factor: 5.594

5.  Building towards precision medicine: empowering medical professionals for the next revolution.

Authors:  Scott McGrath; Dario Ghersi
Journal:  BMC Med Genomics       Date:  2016-05-10       Impact factor: 3.063

Review 6.  Personalized medicine in Europe: not yet personal enough?

Authors:  Antonello Di Paolo; François Sarkozy; Bettina Ryll; Uwe Siebert
Journal:  BMC Health Serv Res       Date:  2017-04-19       Impact factor: 2.655

7.  Current issues in medically assisted reproduction and genetics in Europe: research, clinical practice, ethics, legal issues and policy. European Society of Human Genetics and European Society of Human Reproduction and Embryology.

Authors:  Joyce C Harper; Joep Geraedts; Pascal Borry; Martina C Cornel; Wybo Dondorp; Luca Gianaroli; Gary Harton; Tanya Milachich; Helena Kääriäinen; Inge Liebaers; Michael Morris; Jorge Sequeiros; Karen Sermon; Françoise Shenfield; Heather Skirton; Sirpa Soini; Claudia Spits; Anna Veiga; Joris Robert Vermeesch; Stéphane Viville; Guido de Wert; Milan Macek
Journal:  Eur J Hum Genet       Date:  2013-11       Impact factor: 4.246

  7 in total

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