Literature DB >> 23093537

Varicocele surgery or embolization: Which is better?

Darby Cassidy1, Keith Jarvi, Ethan Grober, Kirk Lo.   

Abstract

INTRODUCTION: : Varicocele remains the most commonly identified correctable cause of male factor infertility. Surgical correction is the most commonly performed technique to treat varicoceles with a technical failure rate of less than 5%. An attractive alternative to surgery is the selective catheterization and embolization of the gonadal vein. This data are limited by small series.
METHODS: : We reviewed a total of 158 patients. These patients underwent embolization for clinical varicoceles and male factor infertility between 2004 and 2008. Of these, 56% underwent attempted bilateral embolization, 43% unilateral left-sided embolization and 1.3% unilateral right-sided embolization.
RESULTS: : Of these patients who underwent attempted bilateral embolization, 19.3% did not experience a successful obliteration of the right gonadal vein and 2.3% (2/88) experienced a failure rate in the embolization of the left gonadal vein. Of the 2 attempts at unilateral right-sided embolization, there were no failures. Of the 68 unilateral left-sided embolization attempts, there was a 4.4% failure rate. Of all of the right-sided embolization attempts, 18.9% failed, while 3.2% of the left-sided attempts failed.
CONCLUSION: : This review represents the largest contemporary series of varicocele embolization outcomes currently in the literature. Our 19.3% technical failure rate for bilateral varicocele embolization is higher than the current published rate of 13% and is largely related to failure to successfully occlude the right gonadal vein. This supports our belief that bilateral varicoceles are best managed with a primary microsurgical approach, where technical failure rates are expected to be less than 5% based on published data. Men with unilateral left-sided varicoceles should be offered both options as they have similar failure rates, but with embolization offering some clear advantages to the patient.

Entities:  

Year:  2012        PMID: 23093537      PMCID: PMC3433543          DOI: 10.5489/cuaj.11064

Source DB:  PubMed          Journal:  Can Urol Assoc J        ISSN: 1911-6470            Impact factor:   1.862


  8 in total

Review 1.  Effects of varicocele on male fertility.

Authors:  J P Jarow
Journal:  Hum Reprod Update       Date:  2001 Jan-Feb       Impact factor: 15.610

2.  Initial experience with percutaneous selective embolization: A truly minimally invasive treatment of the adolescent varicocele with no risk of hydrocele development.

Authors:  Douglas W Storm; Mark J Hogan; Venkata R Jayanthi
Journal:  J Pediatr Urol       Date:  2010-02-11       Impact factor: 1.830

3.  Surgical therapy of male infertility.

Authors:  M Goldstein
Journal:  J Urol       Date:  1993-05       Impact factor: 7.450

4.  The influence of varicocele on parameters of fertility in a large group of men presenting to infertility clinics. World Health Organization.

Authors: 
Journal:  Fertil Steril       Date:  1992-06       Impact factor: 7.329

5.  Varicocele: a progressive or static lesion?

Authors:  M A Witt; L I Lipshultz
Journal:  Urology       Date:  1993-11       Impact factor: 2.649

Review 6.  [Varicocele and its repercussion on infertility. Indications and limitations of surgical intervention].

Authors:  E Austoni; A Cazzaniga; G Gatti; P Baroni; O Gentilini; C A Levorato
Journal:  Arch Ital Urol Androl       Date:  1998-04

Review 7.  Treatment of palpable varicocele in infertile men: a meta-analysis to define the best technique.

Authors:  Selahittin Cayan; Shavkat Shavakhabov; Ateş Kadioğlu
Journal:  J Androl       Date:  2008-09-04

8.  Subinguinal microsurgical varicocelectomy: evaluation of the results.

Authors:  Rajeev Kumar; Narmada P Gupta
Journal:  Urol Int       Date:  2003       Impact factor: 2.089

  8 in total
  13 in total

Review 1.  Image-Guided Treatment of Varicoceles: A Brief Literature Review and Technical Note.

Authors:  Reza Talaie; Shamar J Young; Prashant Shrestha; Siobhan M Flanagan; Michael S Rosenberg; Jafar Golzarian
Journal:  Semin Intervent Radiol       Date:  2016-09       Impact factor: 1.513

2.  Radiation dose reduction in fluoroscopic procedures: left varicocele embolization as a model.

Authors:  Anthony G Verstandig; Bashar Shamieh; Vladimir Shraibman; David Raveh
Journal:  Eur Radiol       Date:  2014-12-19       Impact factor: 5.315

3.  Cost-effectiveness analysis reveals microsurgical varicocele repair is superior to percutaneous embolization in the treatment of male infertility.

Authors:  Jason Ronald Kovac; Jake Fantus; Larry I Lipshultz; Marc Anthony Fischer; Zachery Klinghoffer
Journal:  Can Urol Assoc J       Date:  2014-09       Impact factor: 1.862

4.  Case - Laparoscopic excision of the right testicular vein post-varicocele embolization and coil erosion.

Authors:  Bartosz Orzel; John-Paul McCarthy; Kenneth Rent
Journal:  Can Urol Assoc J       Date:  2021-08-26       Impact factor: 1.862

5.  Varicocele percutaneous embolization outcomes in a pediatric group: 7-year retrospective study.

Authors:  Sonaz Malekzadeh; Rodrigo A Fraga-Silva; Pierre-Henri Morère; Alexandra Sorega; Stephan Produit; Nikolaos Stergiopulos; Christophe Constantin
Journal:  Int Urol Nephrol       Date:  2016-06-30       Impact factor: 2.370

Review 6.  [Interventional treatment of benign prostatic hyperplasia : Embolization of the testicular vein].

Authors:  M Rauch; H Strunk
Journal:  Radiologe       Date:  2017-08       Impact factor: 0.635

7.  Surgical or radiological treatment for varicoceles in subfertile men.

Authors:  Emma Persad; Clare Aa O'Loughlin; Simi Kaur; Gernot Wagner; Nina Matyas; Melanie Rosalia Hassler-Di Fratta; Barbara Nussbaumer-Streit
Journal:  Cochrane Database Syst Rev       Date:  2021-04-23

8.  Mutation analysis of TNP1 gene in infertile men with varicocele.

Authors:  Mohammad Mehdi Heidari; Mehri Khatami; Ali Reza Talebi; Fahime Moezzi
Journal:  Iran J Reprod Med       Date:  2014-04

Review 9.  Percutaneous embolization of varicocele: technique, indications, relative contraindications, and complications.

Authors:  Joshua Halpern; Sameer Mittal; Keith Pereira; Shivank Bhatia; Ranjith Ramasamy
Journal:  Asian J Androl       Date:  2016 Mar-Apr       Impact factor: 3.285

Review 10.  The role of microsurgical varicocelectomy in treating male infertility.

Authors:  Alexander J Tatem; Robert E Brannigan
Journal:  Transl Androl Urol       Date:  2017-08
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