Literature DB >> 23090329

Physical activity: an essential component of lifestyle modification in NAFLD.

Benjamin Rodriguez1, Dawn M Torres, Stephen A Harrison.   

Abstract

NAFLD encompasses a spectrum of liver diseases pertaining to fat accumulation in the liver in the absence of significant alcohol consumption. NASH is the most clinically relevant subset of NAFLD, and patients with NASH have an increased risk of progression to cirrhosis or developing liver cancer. No pharmacotherapy is currently approved for NAFLD, and lifestyle modification via diet and exercise is most commonly recommended. The optimal physical activity regimen in terms of both effectiveness and compliance remains to be determined and is the focus of this Review.

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Year:  2012        PMID: 23090329     DOI: 10.1038/nrgastro.2012.200

Source DB:  PubMed          Journal:  Nat Rev Gastroenterol Hepatol        ISSN: 1759-5045            Impact factor:   46.802


  25 in total

Review 1.  Exercise and non-alcoholic fatty liver disease: a systematic review and meta-analysis.

Authors:  Shelley E Keating; Daniel A Hackett; Jacob George; Nathan A Johnson
Journal:  J Hepatol       Date:  2012-03-10       Impact factor: 25.083

Review 2.  Resistance training in the treatment of the metabolic syndrome: a systematic review and meta-analysis of the effect of resistance training on metabolic clustering in patients with abnormal glucose metabolism.

Authors:  Barbara Strasser; Uwe Siebert; Wolfgang Schobersberger
Journal:  Sports Med       Date:  2010-05-01       Impact factor: 11.136

3.  Sitting time and all-cause mortality risk in 222 497 Australian adults.

Authors:  Hidde P van der Ploeg; Tien Chey; Rosemary J Korda; Emily Banks; Adrian Bauman
Journal:  Arch Intern Med       Date:  2012-03-26

4.  Effect of exercise and dietary modification on serum aminotransferase levels in patients with nonalcoholic steatohepatitis.

Authors:  Chalamalasetty Sreenivasa Baba; George Alexander; Bikkasani Kalyani; Rakesh Pandey; Sujata Rastogi; Amaresh Pandey; Gourdas Choudhuri
Journal:  J Gastroenterol Hepatol       Date:  2006-01       Impact factor: 4.029

5.  Orlistat for overweight subjects with nonalcoholic steatohepatitis: A randomized, prospective trial.

Authors:  Stephen A Harrison; Will Fecht; Elizabeth M Brunt; Brent A Neuschwander-Tetri
Journal:  Hepatology       Date:  2009-01       Impact factor: 17.425

6.  Effect of a 12-month intensive lifestyle intervention on hepatic steatosis in adults with type 2 diabetes.

Authors:  Mariana Lazo; Steven F Solga; Alena Horska; Susanne Bonekamp; Anna Mae Diehl; Frederick L Brancati; Lynne E Wagenknecht; F Xavier Pi-Sunyer; Steven E Kahn; Jeanne M Clark
Journal:  Diabetes Care       Date:  2010-07-27       Impact factor: 19.112

7.  Aerobic exercise training reduces hepatic and visceral lipids in obese individuals without weight loss.

Authors:  Nathan A Johnson; Toos Sachinwalla; David W Walton; Kate Smith; Ashley Armstrong; Martin W Thompson; Jacob George
Journal:  Hepatology       Date:  2009-10       Impact factor: 17.425

8.  Dietary fat and carbohydrates differentially alter insulin sensitivity during caloric restriction.

Authors:  Erik Kirk; Dominic N Reeds; Brian N Finck; S Mitra Mayurranjan; Mitra S Mayurranjan; Bruce W Patterson; Samuel Klein
Journal:  Gastroenterology       Date:  2009-01-25       Impact factor: 22.682

9.  Role of leisure-time physical activity in nonalcoholic fatty liver disease: a population-based study.

Authors:  Shira Zelber-Sagi; Dorit Nitzan-Kaluski; Rebecca Goldsmith; Muriel Webb; Izabel Zvibel; Ilana Goldiner; Laurie Blendis; Zamir Halpern; Ran Oren
Journal:  Hepatology       Date:  2008-12       Impact factor: 17.425

10.  Short-term exercise reduces markers of hepatocyte apoptosis in nonalcoholic fatty liver disease.

Authors:  Ciaran E Fealy; Jacob M Haus; Thomas P J Solomon; Mangesh Pagadala; Chris A Flask; Arthur J McCullough; John P Kirwan
Journal:  J Appl Physiol (1985)       Date:  2012-05-10
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  15 in total

Review 1.  Effects of physical activity upon the liver.

Authors:  Roy J Shephard; Nathan Johnson
Journal:  Eur J Appl Physiol       Date:  2014-11-04       Impact factor: 3.078

2.  EASL-EASD-EASO Clinical Practice Guidelines for the management of non-alcoholic fatty liver disease.

Authors: 
Journal:  Diabetologia       Date:  2016-06       Impact factor: 10.122

3.  Sparstolonin B attenuates early liver inflammation in experimental NASH by modulating TLR4 trafficking in lipid rafts via NADPH oxidase activation.

Authors:  Diptadip Dattaroy; Ratanesh Kumar Seth; Suvarthi Das; Firas Alhasson; Varun Chandrashekaran; Gregory Michelotti; Daping Fan; Mitzi Nagarkatti; Prakash Nagarkatti; Anna Mae Diehl; Saurabh Chatterjee
Journal:  Am J Physiol Gastrointest Liver Physiol       Date:  2015-12-30       Impact factor: 4.052

4.  Reduced hepatic eNOS phosphorylation is associated with NAFLD and type 2 diabetes progression and is prevented by daily exercise in hyperphagic OLETF rats.

Authors:  Ryan D Sheldon; M Harold Laughlin; R Scott Rector
Journal:  J Appl Physiol (1985)       Date:  2014-02-27

5.  Intrinsic aerobic capacity impacts susceptibility to acute high-fat diet-induced hepatic steatosis.

Authors:  E Matthew Morris; Matthew R Jackman; Ginger C Johnson; Tzu-Wen Liu; Jordan L Lopez; Monica L Kearney; Justin A Fletcher; Grace M E Meers; Lauren G Koch; Stephen L Britton; R Scott Rector; Jamal A Ibdah; Paul S MacLean; John P Thyfault
Journal:  Am J Physiol Endocrinol Metab       Date:  2014-06-24       Impact factor: 4.310

6.  Voluntary exercise under a food restriction condition decreases blood branched-chain amino acid levels, in addition to improvement of glucose and lipid metabolism, in db mice, animal model of type 2 diabetes.

Authors:  Ancah Caesarina Novi Marchianti; Emi Arimura; Miharu Ushikai; Masahisa Horiuchi
Journal:  Environ Health Prev Med       Date:  2014-08-02       Impact factor: 3.674

7.  Coffee consumption in NAFLD patients with lower insulin resistance is associated with lower risk of severe fibrosis.

Authors:  Kiran Bambha; Laura A Wilson; Aynur Unalp; Rohit Loomba; Brent A Neuschwander-Tetri; Elizabeth M Brunt; Nathan M Bass
Journal:  Liver Int       Date:  2013-11-24       Impact factor: 5.828

8.  Hepatic steatosis and steatohepatitis: Are they really two distinct entities?

Authors:  Cory M Fielding; Paul Angulo
Journal:  Curr Hepatol Rep       Date:  2014-06-01

9.  Sympathetic nervous system catecholamines and neuropeptide Y neurotransmitters are upregulated in human NAFLD and modulate the fibrogenic function of hepatic stellate cells.

Authors:  Barbara Sigala; Chad McKee; Junpei Soeda; Valerio Pazienza; Maelle Morgan; Ching-I Lin; Clare Selden; Sara Vander Borght; Gianluigi Mazzoccoli; Tania Roskams; Manlio Vinciguerra; Jude A Oben
Journal:  PLoS One       Date:  2013-09-03       Impact factor: 3.240

10.  EASL-EASD-EASO Clinical Practice Guidelines for the Management of Non-Alcoholic Fatty Liver Disease.

Authors: 
Journal:  Obes Facts       Date:  2016-04-08       Impact factor: 3.942

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