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Literature DB >> 23085873

Advancing pharmacometrics and systems pharmacology.

Abstract

Pharmacometrics and systems pharmacology are emerging as principal quantitative sciences within drug development and experimental therapeutics. In recognition of the importance of pharmacometrics and systems pharmacology to the discipline of clinical pharmacology, the American Society for Clinical Pharmacology and Therapeutics (ASCPT), in collaboration with Nature Publishing Group and Clinical Pharmacology & Therapeutics, has established CPT: Pharmacometrics & Systems Pharmacology to inform the field and shape the discipline.

Entities: Chemical Disease Gene Species

Mesh：

Year: 2012 PMID： 23085873 PMCID： PMC5540435 DOI： 10.1038/clpt.2012.151

Source DB: PubMed Journal: Clin Pharmacol Ther ISSN： 0009-9236 Impact factor: 6.875

12 in total

1. Models of physiology and physiologically based models in clinical pharmacology.

Authors: A J Atkinson; B P Smith
Journal: Clin Pharmacol Ther Date: 2012-07 Impact factor: 6.875

2. Molecular therapeutics from knowledge to delivery.

Authors: S A Waldman; A Terzic
Journal: Clin Pharmacol Ther Date: 2010-06 Impact factor: 6.875

Review 3. Systems biology: an approach.

Authors: P Kohl; E J Crampin; T A Quinn; D Noble
Journal: Clin Pharmacol Ther Date: 2010-06-09 Impact factor: 6.875

Review 4. Next-generation model-based drug discovery and development: quantitative and systems pharmacology.

Authors: S R B Allerheiligen
Journal: Clin Pharmacol Ther Date: 2010-06-09 Impact factor: 6.875

Review 5. Multiscale modeling in drug discovery and development: future opportunities and present challenges.

Authors: P Vicini
Journal: Clin Pharmacol Ther Date: 2010-06-02 Impact factor: 6.875

Review 6. Network systems biology for drug discovery.

Authors: D K Arrell; A Terzic
Journal: Clin Pharmacol Ther Date: 2010-06-02 Impact factor: 6.875

Review 7. Improving productivity with model-based drug development: an enterprise perspective.

Authors: T H Grasela; R Slusser
Journal: Clin Pharmacol Ther Date: 2010-06-30 Impact factor: 6.875

8. Systems clinical pharmacology.

Authors: A J Atkinson; P M Lyster
Journal: Clin Pharmacol Ther Date: 2010-07 Impact factor: 6.875

9. The challenge of complexity.

Authors: C T Dollery
Journal: Clin Pharmacol Ther Date: 2010-07 Impact factor: 6.875

10. CPT: Pharmacometrics and Systems Pharmacology.

Authors: Piet H van der Graaf
Journal: CPT Pharmacometrics Syst Pharmacol Date: 2012-09-26

4 in total

1. Companion diagnostics at the intersection of personalized medicine and healthcare delivery.

Authors: Scott A Waldman; Andre Terzic
Journal: Biomark Med Date: 2015 Impact factor: 2.851

Review 2. How drugs get into cells: tested and testable predictions to help discriminate between transporter-mediated uptake and lipoidal bilayer diffusion.

Authors: Douglas B Kell; Stephen G Oliver
Journal: Front Pharmacol Date: 2014-10-31 Impact factor: 5.810

3. Enhancing Drug Efficacy and Therapeutic Index through Cheminformatics-Based Selection of Small Molecule Binary Weapons That Improve Transporter-Mediated Targeting: A Cytotoxicity System Based on Gemcitabine.

Authors: Justine M Grixti; Steve O'Hagan; Philip J Day; Douglas B Kell
Journal: Front Pharmacol Date: 2017-03-27 Impact factor: 5.810

4. Systems approaches evolve clinical pharmacology.

Authors: S A Waldman; P H van der Graaf; A Terzic
Journal: CPT Pharmacometrics Syst Pharmacol Date: 2013-08-21

4 in total