| Literature DB >> 23081814 |
M J Binnicker1, D J Jespersen, J E Bestrom, L O Rollins.
Abstract
We compared the performance of four assays for the detection of cryptococcal antigen in serum samples (n = 634) and cerebrospinal fluid (CSF) samples (n = 51). Compared to latex agglutination, the sensitivity and specificity of the Premier enzyme immunoassay (EIA), Alpha CrAg EIA, and CrAg lateral flow assay (LFA) were 55.6 and 100%, 100 and 99.7%, and 100 and 99.8%, respectively, from serum samples. There was 100% agreement among the four tests for CSF samples, with 18 samples testing positive by each of the assays.Entities:
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Year: 2012 PMID: 23081814 PMCID: PMC3535868 DOI: 10.1128/CVI.00446-12
Source DB: PubMed Journal: Clin Vaccine Immunol ISSN: 1556-679X