| Literature DB >> 23079652 |
Abstract
The childhood cancer embryonal rhabdomyosarcoma can arise in tissue without skeletal muscle elements. In this issue of Cancer Cell, Hatley and colleagues report that non-skeletal muscle progenitors can be a cell of origin for Sonic Hedgehog-driven embryonal rhabdomyosarcoma in an adipocyte-restricted conditional mouse model.Entities:
Year: 2012 PMID: 23079652 PMCID: PMC3486430 DOI: 10.1016/j.ccr.2012.09.018
Source DB: PubMed Journal: Cancer Cell ISSN: 1535-6108 Impact factor: 31.743