Literature DB >> 23079590

High-resolution homonuclear 2D NMR of carbon-13 enriched metabolites and their mixtures.

Fengli Zhang1, Lei Bruschweiler-Li, Rafael Brüschweiler.   

Abstract

High-resolution 2D (13)C-(13)C NMR correlation spectra of uniformly (13)C-labeled molecules in solution are obtained by homonuclear (13)C-decoupling along both dimensions by the application of indirect covariance NMR to constant-time NMR spectra. The spectra are optimally suited for chemical structure elucidation and molecular identification of the components of complex mixtures, such as ones from uniformly (13)C-labeled cell cultures.
Copyright © 2012 Elsevier Inc. All rights reserved.

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Year:  2012        PMID: 23079590      PMCID: PMC3783953          DOI: 10.1016/j.jmr.2012.09.006

Source DB:  PubMed          Journal:  J Magn Reson        ISSN: 1090-7807            Impact factor:   2.229


  22 in total

1.  A novel strategy for the assignment of side-chain resonances in completely deuterated large proteins using 13C spectroscopy.

Authors:  Alexander Eletsky; Osvaldo Moreira; Helena Kovacs; Konstantin Pervushin
Journal:  J Biomol NMR       Date:  2003-06       Impact factor: 2.835

2.  Covariance NMR spectroscopy by singular value decomposition.

Authors:  Nikola Trbovic; Serge Smirnov; Fengli Zhang; Rafael Brüschweiler
Journal:  J Magn Reson       Date:  2004-12       Impact factor: 2.229

3.  True chemical shift correlation maps: a TOCSY experiment with pure shifts in both dimensions.

Authors:  Gareth A Morris; Juan A Aguilar; Robert Evans; Stephan Haiber; Mathias Nilsson
Journal:  J Am Chem Soc       Date:  2010-09-22       Impact factor: 15.419

4.  Enhanced covariance spectroscopy from minimal datasets.

Authors:  Yanbin Chen; Fengli Zhang; Wolfgang Bermel; Rafael Brüschweiler
Journal:  J Am Chem Soc       Date:  2006-12-13       Impact factor: 15.419

5.  Integration of spin-state-selective excitation into 2D NMR correlation experiments with the heteronuclear ZQ/2Q pi rotations for 1JXH- resolved E.COSY-type measurements of heteronuclear coupling constants in proteins.

Authors:  A Meissner; J O Duus; O W Sørensen
Journal:  J Biomol NMR       Date:  1997-07       Impact factor: 2.835

6.  Multisite band-selective decoupling in proteins.

Authors:  E Kupce; G Wagner
Journal:  J Magn Reson B       Date:  1996-03

Review 7.  Measurement of J and dipolar couplings from simplified two-dimensional NMR spectra.

Authors:  M Ottiger; F Delaglio; A Bax
Journal:  J Magn Reson       Date:  1998-04       Impact factor: 2.229

8.  NMRPipe: a multidimensional spectral processing system based on UNIX pipes.

Authors:  F Delaglio; S Grzesiek; G W Vuister; G Zhu; J Pfeifer; A Bax
Journal:  J Biomol NMR       Date:  1995-11       Impact factor: 2.835

9.  Carbon backbone topology of the metabolome of a cell.

Authors:  Kerem Bingol; Fengli Zhang; Lei Bruschweiler-Li; Rafael Brüschweiler
Journal:  J Am Chem Soc       Date:  2012-05-17       Impact factor: 15.419

10.  Cryogenic probe 13C NMR spectroscopy of urine for metabonomic studies.

Authors:  Hector C Keun; Olaf Beckonert; Julian L Griffin; Christian Richter; Detlef Moskau; John C Lindon; Jeremy K Nicholson
Journal:  Anal Chem       Date:  2002-09-01       Impact factor: 6.986

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  4 in total

Review 1.  Can NMR solve some significant challenges in metabolomics?

Authors:  G A Nagana Gowda; Daniel Raftery
Journal:  J Magn Reson       Date:  2015-08-18       Impact factor: 2.229

Review 2.  Multidimensional approaches to NMR-based metabolomics.

Authors:  Kerem Bingol; Rafael Brüschweiler
Journal:  Anal Chem       Date:  2013-11-22       Impact factor: 6.986

3.  ¹³C NMR metabolomics: applications at natural abundance.

Authors:  Chaevien S Clendinen; Brittany Lee-McMullen; Caroline M Williams; Gregory S Stupp; Krista Vandenborne; Daniel A Hahn; Glenn A Walter; Arthur S Edison
Journal:  Anal Chem       Date:  2014-08-29       Impact factor: 6.986

4.  NMR-Based Metabolomics.

Authors:  G A Nagana Gowda; Daniel Raftery
Journal:  Adv Exp Med Biol       Date:  2021       Impact factor: 2.622

  4 in total

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