| Literature DB >> 23077003 |
Yeon-Ju Lee1, Su-Jung Yoo, Jong Soon Kang, Jieun Yun, Hee Jae Shin, Jong Seok Lee, Hyi-Seung Lee.
Abstract
A novel petrosiacetylene analog (petrosiacetylene E) has been isolated from the Korean marine sponge Petrosia sp., along with petrosiacetylene A, B and C. Their structures were elucidated on the basis of spectroscopic methods and the stereochemistry of the new compound was determined by using the modified Mosher's method. Petrosiacetylene E showed higher cytotoxicity against five human cancer cell lines than petrosiacetylene A and B, presumably due to the additional hydroxy group located at C-16.Entities:
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Year: 2012 PMID: 23077003 DOI: 10.1007/s11745-012-3727-5
Source DB: PubMed Journal: Lipids ISSN: 0024-4201 Impact factor: 1.880