| Literature DB >> 17985844 |
Chikane Okamoto1, Yoichi Nakao, Tsuyoshi Fujita, Takashi Iwashita, Rob W M van Soest, Nobuhiro Fusetani, Shigeki Matsunaga.
Abstract
Two new polyacetylene carboxylic acids, petroformynic acids B (3) and C (4), were isolated from a marine sponge Pertrosia sp. as cytotoxic constituents. Their structures were determined by interpretation of 2D NMR data and tandem FABMS data. Absolute stereochemistry of 3 was assigned by application of the modified Mosher analysis. Petroformynic acids exhibit moderate cytotoxic activity against P388 cells.Entities:
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Year: 2007 PMID： 17985844 DOI： 10.1021/np0702943
Source DB: PubMed Journal: J Nat Prod ISSN： 0163-3864 Impact factor: 4.050