Literature DB >> 23076412

The volumetric analysis of fat graft survival in breast reconstruction.

Mihye Choi1, Kevin Small, Chaya Levovitz, Christina Lee, Ahmed Fadl, Nolan S Karp.   

Abstract

BACKGROUND: Fat grafting has emerged as a useful method for breast contouring in aesthetic and reconstructive patients. Advancements have been made in fat graft harvest and delivery, but the ability to judge the overall success of fat grafting remains limited. The authors applied three-dimensional imaging technology to assess volumetric fat graft survival following autologous fat transfer to the breast.
METHODS: Fat grafting surgery was performed using a modified Coleman technique in breast reconstruction. Patients undergoing the procedure were entered into the study prospectively and followed. Three-dimensional imaging was performed using the Canfield Vectra system and analyzed using Geomagic software. Breasts were isolated as closed objects, and total breast volume was calculated on every scan.
RESULTS: The data stratified patients into three groups with statistically significant parameters based on the volume of fat injected. The largest injected group (average volume, 151 cc) retained a volume of 86.9 percent (7 days postoperatively), 81.1 percent (16 days), 57.5 percent (49 days), and 52.3 percent (140 days). The smallest group (average, 51 cc) retained a volume of 87.9 percent (7 days postoperatively), 75.8 percent (16 days), 56.6 percent (49 days), and 27.1 percent (140 days). The intermediate group (average, 93 cc) retained 90.3 percent (7 days postoperatively), 74 percent (16 days), 45.7 percent (49 days), and 38.1 percent (140 days). Of note, irradiation or prior breast procedure type did not seem to affect the volume retention rate.
CONCLUSIONS: The authors' data suggest that fat retention is volume and time dependent. Patients receiving higher volumes of injected fat had slower volume loss and greater total volume retention.

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Year:  2013        PMID: 23076412     DOI: 10.1097/PRS.0b013e3182789b13

Source DB:  PubMed          Journal:  Plast Reconstr Surg        ISSN: 0032-1052            Impact factor:   4.730


  45 in total

1.  Autologous Fat Graft in the Reconstructed Breast: Fat Absorption Rate and Safety based on Sonographic Identification.

Authors:  Hong Youl Kim; Bok Ki Jung; Dae Hyun Lew; Dong Won Lee
Journal:  Arch Plast Surg       Date:  2014-11-03

2.  Contrast-enhanced ultrasonography evaluation after autologous fat grafting in scar revision.

Authors:  D Bollero; S Pozza; E N Gangemi; A De Marchi; J Ganem; El Khatib A M; C Faletti; M Stella
Journal:  G Chir       Date:  2014 Nov-Dec

Review 3.  Fat grafting and breast reconstruction: tips for ensuring predictability.

Authors:  Allen Gabriel; Manish C Champaneria; G Patrick Maxwell
Journal:  Gland Surg       Date:  2015-06

Review 4.  Autologous Fat Grafting: The Science Behind the Surgery.

Authors:  Elizabeth R Zielins; Elizabeth A Brett; Michael T Longaker; Derrick C Wan
Journal:  Aesthet Surg J       Date:  2016-04       Impact factor: 4.283

5.  Autologous fat transplantation for secondary breast reconstruction: our experience.

Authors:  F Simonacci; M P Grieco; N Bertozzi; E Raposio
Journal:  G Chir       Date:  2017 May-Jun

6.  The role of fat grafting in prepectoral breast reconstruction.

Authors:  Halley Darrach; Franca Kraenzlin; Nima Khavanin; Karan Chopra; Justin M Sacks
Journal:  Gland Surg       Date:  2019-02

7.  Combining decellularized human adipose tissue extracellular matrix and adipose-derived stem cells for adipose tissue engineering.

Authors:  Lina Wang; Joshua A Johnson; Qixu Zhang; Elisabeth K Beahm
Journal:  Acta Biomater       Date:  2013-06-29       Impact factor: 8.947

8.  Three-dimensional Volumetric Analysis of 3 Fat-Processing Techniques for Facial Fat Grafting: A Randomized Clinical Trial.

Authors:  Rongwei Wu; Xiaonan Yang; Xiaolei Jin; Haibin Lu; Zhenhua Jia; Binghang Li; Haiyue Jiang; Zuoliang Qi
Journal:  JAMA Facial Plast Surg       Date:  2018-05-01       Impact factor: 4.611

Review 9.  The Current State of Fat Grafting: A Review of Harvesting, Processing, and Injection Techniques.

Authors:  Amy L Strong; Paul S Cederna; J Peter Rubin; Sydney R Coleman; Benjamin Levi
Journal:  Plast Reconstr Surg       Date:  2015-10       Impact factor: 4.730

Review 10.  Effect of Breast Cancer and Adjuvant Therapy on Adipose-Derived Stromal Cells: Implications for the Role of ADSCs in Regenerative Strategies for Breast Reconstruction.

Authors:  Ritihaas Surya Challapalli; Roisin M Dwyer; Niall McInerney; Michael J Kerin; Aoife J Lowery
Journal:  Stem Cell Rev Rep       Date:  2020-09-14       Impact factor: 5.739

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