Literature DB >> 2307140

SAXS study of the snake toxin alpha-crotamine.

J R Beltran1, Y P Mascarenhas, A F Craievich, C J Laure.   

Abstract

alpha-crotamine is a small toxic protein (42 amino acid residues with three disulphide bridges) present in the venom of Crotallus durissus terrificus. Molecular parameters (Rg = 13.7 A, S = 3,000 A2, V = 9,200 A3 and Dmax = 40 A) were derived from SAXS curves obtained from a solution of this protein at pH = 4.5. An excellent agreement between the experimental distance distribution curve and that calculated from a model consisting of two lobes linked by the Cys(18)-Cys(30) disulphide bridge.

Entities:  

Mesh:

Substances:

Year:  1990        PMID: 2307140     DOI: 10.1007/bf00258381

Source DB:  PubMed          Journal:  Eur Biophys J        ISSN: 0175-7571            Impact factor:   1.733


  6 in total

1.  [The primary structure of crotamine (author's transl)].

Authors:  C J Laure
Journal:  Hoppe Seylers Z Physiol Chem       Date:  1975-02

2.  Crotamine conformation: effect of pH and temperature.

Authors:  O G Hampe; M M Vozári-Hampe; J M Gonçalves
Journal:  Toxicon       Date:  1978       Impact factor: 3.033

Review 3.  Empirical predictions of protein conformation.

Authors:  P Y Chou; G D Fasman
Journal:  Annu Rev Biochem       Date:  1978       Impact factor: 23.643

4.  Saxs study of structure and conformational changes of crotamine.

Authors:  J R Beltran; Y P Mascarenhas; A F Craievich; C J Laure
Journal:  Biophys J       Date:  1985-01       Impact factor: 4.033

5.  Small-angle X-ray scattering.

Authors:  I Pilz; O Glatter; O Kratky
Journal:  Methods Enzymol       Date:  1979       Impact factor: 1.600

6.  Beta-turns in proteins.

Authors:  P Y Chou; G D Fasman
Journal:  J Mol Biol       Date:  1977-09-15       Impact factor: 5.469

  6 in total
  4 in total

1.  Structure-function relationship for the highly toxic crotoxin from Crotalus durissus terrificus.

Authors:  Y P Mascarenhas; P F Stouten; J R Beltran; C J Laure; G Vriend
Journal:  Eur Biophys J       Date:  1992       Impact factor: 1.733

Review 2.  Nanobiotechnology with Therapeutically Relevant Macromolecules from Animal Venoms: Venoms, Toxins, and Antimicrobial Peptides.

Authors:  Cesar Augusto Roque-Borda; Marcos William de Lima Gualque; Fauller Henrique da Fonseca; Fernando Rogério Pavan; Norival Alves Santos-Filho
Journal:  Pharmaceutics       Date:  2022-04-19       Impact factor: 6.525

Review 3.  Computational Studies of Snake Venom Toxins.

Authors:  Paola G Ojeda; David Ramírez; Jans Alzate-Morales; Julio Caballero; Quentin Kaas; Wendy González
Journal:  Toxins (Basel)       Date:  2017-12-22       Impact factor: 4.546

4.  Crotamine in Crotalus durissus: distribution according to subspecies and geographic origin, in captivity or nature.

Authors:  Lídia J Tasima; Caroline Serino-Silva; Daniela M Hatakeyama; Erika S Nishiduka; Alexandre K Tashima; Sávio S Sant'Anna; Kathleen F Grego; Karen de Morais-Zani; Anita M Tanaka-Azevedo
Journal:  J Venom Anim Toxins Incl Trop Dis       Date:  2020-04-06
  4 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.