Literature DB >> 23070585

Patients' choice on axillary lymph node dissection following sentinel lymph node micrometastasis--first report on prospective use of a nomogram in very low risk patients.

Gábor Cserni1, Istvánné Bezsenyi, László Markó.   

Abstract

The optimal locoregional treatment of patients diagnosed with sentinel node (SN) micrometastasis is controversial. A previously reported and validated nomogram was used to calculate the risk of non-SN metastasis in patients with SN micrometastasis over a period of 2 years. Patients were given detailed information about the risk, consequences and treatment options of non-SN involvement, the risk and potential complications of unnecessary completion axillary lymph node dissection (ALND), the imperfectness of the nomogram, and other factors that may influence their selection of further treatment. They also received a questionnaire to monitor factors influencing their decisions. Of the 25 patients participating in the study, 10 have opted for ALND. The only factor that seemed to influence their choice was fear from disease recurrence. Giving detailed information to SN micrometastatic patients is a patient-centered alternative to current recommendations on performing ALND in all such patients or omitting ALND in all of them.

Entities:  

Mesh:

Year:  2012        PMID: 23070585     DOI: 10.1007/s12253-012-9571-3

Source DB:  PubMed          Journal:  Pathol Oncol Res        ISSN: 1219-4956            Impact factor:   3.201


  28 in total

1.  Meta-analysis of non-sentinel node metastases associated with micrometastatic sentinel nodes in breast cancer.

Authors:  G Cserni; D Gregori; F Merletti; A Sapino; M P Mano; A Ponti; S Sandrucci; B Baltás; G Bussolati
Journal:  Br J Surg       Date:  2004-10       Impact factor: 6.939

2.  [Modern surgical treatment of breast cancer -- 2nd Consensus Conference].

Authors:  György Lázár; István Besznyák; Gábor Boross; Zoltán Farsang; Gusztáv Gulyás; Ferenc Jakab; Róbert Maráz; Béla Márkus; László Tóth
Journal:  Magy Seb       Date:  2010-06

3.  Do all patients with sentinel node metastasis from breast carcinoma need complete axillary node dissection?

Authors:  K U Chu; R R Turner; N M Hansen; M B Brennan; A Bilchik; A E Giuliano
Journal:  Ann Surg       Date:  1999-04       Impact factor: 12.969

4.  Distinction between isolated tumor cells and micrometastases in breast cancer: is it reliable and useful?

Authors:  Isabelle de Mascarel; Gaetan MacGrogan; Marc Debled; Veronique Brouste; Louis Mauriac
Journal:  Cancer       Date:  2008-04-15       Impact factor: 6.860

5.  A nomogram predictive of non-sentinel lymph node involvement in breast cancer patients with a sentinel lymph node micrometastasis.

Authors:  G Houvenaeghel; C Nos; S Giard; H Mignotte; B Esterni; J Jacquemier; M Buttarelli; J-M Classe; M Cohen; P Rouanet; F Penault Llorca; P Bonnier; F Marchal; J-R Garbay; J Fraisse; P Martel; E Fondrinier; C Tunon de Lara; J-F Rodier
Journal:  Eur J Surg Oncol       Date:  2008-11-28       Impact factor: 4.424

6.  Comparison of sentinel lymph node biopsy alone and completion axillary lymph node dissection for node-positive breast cancer.

Authors:  Karl Y Bilimoria; David J Bentrem; Nora M Hansen; Kevin P Bethke; Alfred W Rademaker; Clifford Y Ko; David P Winchester; David J Winchester
Journal:  J Clin Oncol       Date:  2009-04-13       Impact factor: 44.544

7.  Nodal stage classification for breast carcinoma: improving interobserver reproducibility through standardized histologic criteria and image-based training.

Authors:  Roderick R Turner; Donald L Weaver; Gabor Cserni; Susan C Lester; Karen Hirsch; David A Elashoff; Patrick L Fitzgibbons; Giuseppe Viale; Giovanni Mazzarol; Julio A Ibarra; Stuart J Schnitt; Armando E Giuliano
Journal:  J Clin Oncol       Date:  2008-01-10       Impact factor: 44.544

8.  Multi-institutional comparison of non-sentinel lymph node predictive tools in breast cancer patients with high predicted risk of further axillary metastasis.

Authors:  Gábor Cserni; Rita Bori; Róbert Maráz; Marjut H K Leidenius; Tuomo J Meretoja; Paivi S Heikkila; Peter Regitnig; Gero Luschin-Ebengreuth; Janez Zgajnar; Andraz Perhavec; Barbara Gazic; György Lázár; Tibor Takács; András Vörös; Riccardo A Audisio
Journal:  Pathol Oncol Res       Date:  2012-07-14       Impact factor: 3.201

9.  Strategies for subtypes--dealing with the diversity of breast cancer: highlights of the St. Gallen International Expert Consensus on the Primary Therapy of Early Breast Cancer 2011.

Authors:  A Goldhirsch; W C Wood; A S Coates; R D Gelber; B Thürlimann; H-J Senn
Journal:  Ann Oncol       Date:  2011-06-27       Impact factor: 32.976

10.  Thresholds for therapies: highlights of the St Gallen International Expert Consensus on the primary therapy of early breast cancer 2009.

Authors:  A Goldhirsch; J N Ingle; R D Gelber; A S Coates; B Thürlimann; H-J Senn
Journal:  Ann Oncol       Date:  2009-06-17       Impact factor: 32.976

View more
  1 in total

1.  Regional Disease Control in Selected Patients with Sentinel Lymph Node Involvement and Omission of Axillary Lymph Node Dissection.

Authors:  Gábor Cserni; Róbert Maráz
Journal:  Pathol Oncol Res       Date:  2015-02-04       Impact factor: 3.201

  1 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.