Literature DB >> 23070053

Effect of vocal fold injury location on vibratory parameters in excised canine larynges.

Christopher R Krausert1, Di Ying, Seong Hee Choi, Matthew R Hoffman, Jack J Jiang.   

Abstract

OBJECTIVE: To investigate the effect of vocal fold injury location on vibratory amplitude and lateral phase difference. STUDY
DESIGN: Repeated measures with each excised canine larynx serving as own control.
SETTING: Basic science study conducted in university laboratory.
METHODS: Vocal fold vibration of excised canine larynges was recorded with a high-speed camera before and after inducing vocal fold injury at 1 of 5 locations: anterior, middle, posterior, medial, or superior. Medial and superior injuries were created within the middle third of the vocal fold. Five larynges were used for each of the 5 injury locations. Kymography was performed at the midpoint of the vocal folds for each video. Pre- and postinjury vibratory amplitude and lateral phase difference were compared for each location.
RESULTS: The anterior and medial injuries produced consistent decreases in vibratory amplitude. Middle and posterior injuries might slightly decrease amplitude. Superior injuries seemed to have no effect on amplitude. Anterior and medial injuries induced phase asymmetry between the right and left vocal folds. Middle injuries appeared to affect phase difference slightly, whereas posterior and superior injuries had no effect.
CONCLUSION: Injury to the anterior or medial portions of the vocal fold may be most likely to cause abnormal vocal fold vibration. Using caution in these locations during phonosurgery may favor superior postoperative vocal outcomes.

Entities:  

Mesh:

Year:  2012        PMID: 23070053      PMCID: PMC3593663          DOI: 10.1177/0194599812464336

Source DB:  PubMed          Journal:  Otolaryngol Head Neck Surg        ISSN: 0194-5998            Impact factor:   3.497


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9.  A rat excised larynx model of vocal fold scar.

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10.  In vivo 3D human vocal fold imaging with polarization sensitive optical coherence tomography and a MEMS scanning catheter.

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2.  Classification for animal vocal fold surgery: resection margins impact histological outcomes of vocal fold injury.

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