Literature DB >> 23064836

Advances in molecular imaging of atherosclerosis and myocardial infarction: shedding new light on in vivo cardiovascular biology.

Alkystis Phinikaridou1, Marcelo E Andia, Ajay M Shah, René M Botnar.   

Abstract

Molecular imaging of the cardiovascular system heavily relies on the development of new imaging probes and technologies to facilitate visualization of biological processes underlying or preceding disease. Molecular imaging is a highly active research discipline that has seen tremendous growth over the past decade. It has broadened our understanding of oncologic, neurologic, and cardiovascular diseases by providing new insights into the in vivo biology of disease progression and therapeutic interventions. As it allows for the longitudinal evaluation of biological processes, it is ideally suited for monitoring treatment response. In this review, we will concentrate on the major accomplishments and advances in the field of molecular imaging of atherosclerosis and myocardial infarction with a special focus on magnetic resonance imaging.

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Year:  2012        PMID: 23064836      PMCID: PMC3532533          DOI: 10.1152/ajpheart.00583.2012

Source DB:  PubMed          Journal:  Am J Physiol Heart Circ Physiol        ISSN: 0363-6135            Impact factor:   4.733


  212 in total

1.  A targeted contrast agent for magnetic resonance imaging of thrombus: implications of spatial resolution.

Authors:  L O Johansson; A Bjørnerud; H K Ahlström; D L Ladd; D K Fujii
Journal:  J Magn Reson Imaging       Date:  2001-04       Impact factor: 4.813

2.  Recombinant HDL-like nanoparticles: a specific contrast agent for MRI of atherosclerotic plaques.

Authors:  Juan C Frias; Kevin Jon Williams; Edward A Fisher; Zahi A Fayad
Journal:  J Am Chem Soc       Date:  2004-12-22       Impact factor: 15.419

3.  Evaluation of neovessels in atherosclerotic plaques of rabbits using an albumin-binding intravascular contrast agent and MRI.

Authors:  Jean-Christophe Cornily; Fabien Hyafil; Claudia Calcagno; Karen C Briley-Saebo; James Tunstead; Juan-Gilberto S Aguinaldo; Venkatesh Mani; Vito Lorusso; Friedrich M Cavagna; Zahi A Fayad
Journal:  J Magn Reson Imaging       Date:  2008-06       Impact factor: 4.813

4.  Macrophage myeloperoxidase regulation by granulocyte macrophage colony-stimulating factor in human atherosclerosis and implications in acute coronary syndromes.

Authors:  S Sugiyama; Y Okada; G K Sukhova; R Virmani; J W Heinecke; P Libby
Journal:  Am J Pathol       Date:  2001-03       Impact factor: 4.307

5.  Characterization and in vitro and in vivo testing of CB2-receptor- and NGAL-targeted paramagnetic micelles for molecular MRI of vulnerable atherosclerotic plaque.

Authors:  Bernard C M te Boekhorst; Sandra M Bovens; Juan Rodrigues-Feo; Honorius M H F Sanders; C W A van de Kolk; Antonius I P M de Kroon; Maarten-Jan M Cramer; Pieter A F M Doevendans; Michiel ten Hove; Gerard Pasterkamp; Cees J A van Echteld
Journal:  Mol Imaging Biol       Date:  2010-12       Impact factor: 3.488

Review 6.  Atherosclerotic plaque progression and vulnerability to rupture: angiogenesis as a source of intraplaque hemorrhage.

Authors:  Renu Virmani; Frank D Kolodgie; Allen P Burke; Aloke V Finn; Herman K Gold; Thomas N Tulenko; Steven P Wrenn; Jagat Narula
Journal:  Arterioscler Thromb Vasc Biol       Date:  2005-07-21       Impact factor: 8.311

7.  Comparison of the inflammatory burden of truly asymptomatic carotid atheroma with atherosclerotic plaques contralateral to symptomatic carotid stenosis: an ultra small superparamagnetic iron oxide enhanced magnetic resonance study.

Authors:  Tjun Y Tang; Simon P S Howarth; Sam R Miller; Martin J Graves; Jean-Marie U-King-Im; Rikin A Trivedi; Zhi Yong Li; Stewart R Walsh; Andrew P Brown; Peter J Kirkpatrick; Michael E Gaunt; Jonathan H Gillard
Journal:  J Neurol Neurosurg Psychiatry       Date:  2007-06-19       Impact factor: 10.154

8.  Rapid-clearance iron nanoparticles for inflammation imaging of atherosclerotic plaque: initial experience in animal model.

Authors:  Monica Sigovan; Loic Boussel; Abdulrazzaq Sulaiman; Dominique Sappey-Marinier; Hasan Alsaid; Catherine Desbleds-Mansard; Danielle Ibarrola; Delphine Gamondès; Claire Corot; Eric Lancelot; Jean-Sebastian Raynaud; Véronique Vives; Christine Laclédère; Xavier Violas; Philippe C Douek; Emmanuelle Canet-Soulas
Journal:  Radiology       Date:  2009-08       Impact factor: 11.105

9.  A leukocyte-mimetic magnetic resonance imaging contrast agent homes rapidly to activated endothelium and tracks with atherosclerotic lesion macrophage content.

Authors:  Martina A McAteer; Kulveer Mankia; Neil Ruparelia; Andrew Jefferson; Hannah B Nugent; Lee-Anne Stork; Keith M Channon; Jurgen E Schneider; Robin P Choudhury
Journal:  Arterioscler Thromb Vasc Biol       Date:  2012-04-12       Impact factor: 8.311

10.  Detection of thrombus size and protein content by ex vivo magnetization transfer and diffusion weighted MRI.

Authors:  Alkystis Phinikaridou; Ye Qiao; Nick Giordano; James A Hamilton
Journal:  J Cardiovasc Magn Reson       Date:  2012-06-25       Impact factor: 5.364

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  5 in total

1.  A histone H1-binding-aptide-based apoptosis imaging probe for monitoring tumor responses to cancer therapy.

Authors:  Yonghyun Lee; Sunghyun Kim; Daejin Kim; Sangyong Jon
Journal:  Medchemcomm       Date:  2017-01-05       Impact factor: 3.597

2.  In vivo molecular imaging of apoptosis and necrosis in atherosclerotic plaques using microSPECT-CT and microPET-CT imaging.

Authors:  M De Saint-Hubert; M Bauwens; N Deckers; M Drummen; K Douma; P Granton; G Hendrikx; D Kusters; J Bucerius; C P M Reutelingsperger; F M Mottaghy
Journal:  Mol Imaging Biol       Date:  2014-04       Impact factor: 3.488

Review 3.  Molecular imaging of inflammation in atherosclerosis.

Authors:  Moritz Wildgruber; Filip K Swirski; Alma Zernecke
Journal:  Theranostics       Date:  2013-11-01       Impact factor: 11.556

Review 4.  Recent advances in molecular magnetic resonance imaging of liver fibrosis.

Authors:  Zhiming Li; Jihong Sun; Xiaoming Yang
Journal:  Biomed Res Int       Date:  2015-03-22       Impact factor: 3.411

Review 5.  Endothelial-Vascular Smooth Muscle Cells Interactions in Atherosclerosis.

Authors:  Manna Li; Ming Qian; Kathy Kyler; Jian Xu
Journal:  Front Cardiovasc Med       Date:  2018-10-23
  5 in total

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