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Literature DB >> 23061667

Nickel-mediated oxidative fluorination for PET with aqueous [18F] fluoride.

Eunsung Lee¹, Jacob M Hooker, Tobias Ritter.

Abstract

A one-step oxidative fluorination for carbon-fluorine bond formation from well-defined nickel complexes with oxidant and aqueous fluoride is presented, which enables a straightforward and practical (18)F late-stage fluorination of complex small molecules with potential for PET imaging.

Entities: Chemical Gene

Mesh：

Substances：

Year: 2012 PMID： 23061667 PMCID： PMC3494465 DOI： 10.1021/ja3084797

Source DB: PubMed Journal: J Am Chem Soc ISSN： 0002-7863 Impact factor: 15.419

21 in total

1. Palladium-mediated fluorination of arylboronic acids.

Authors: Takeru Furuya; Hanns Martin Kaiser; Tobias Ritter
Journal: Angew Chem Int Ed Engl Date: 2008 Impact factor: 15.336

Review 2. Synthesis of 11C, 18F, 15O, and 13N radiolabels for positron emission tomography.

Authors: Philip W Miller; Nicholas J Long; Ramon Vilar; Antony D Gee
Journal: Angew Chem Int Ed Engl Date: 2008 Impact factor: 15.336

Review 3. Molecular imaging with PET.

Authors: Simon M Ametamey; Michael Honer; Pius August Schubiger
Journal: Chem Rev Date: 2008-04-22 Impact factor: 60.622

4. Fast and high-yield microreactor syntheses of ortho-substituted [(18)F]fluoroarenes from reactions of [(18)F]fluoride ion with diaryliodonium salts.

Authors: Joong-Hyun Chun; Shuiyu Lu; Yong-Sok Lee; Victor W Pike
Journal: J Org Chem Date: 2010-05-21 Impact factor: 4.354

Nickel-mediated oxidative fluorination for PET with aqueous [18F] fluoride.

1. Palladium-mediated fluorination of arylboronic acids.

Review 2. Synthesis of 11C, 18F, 15O, and 13N radiolabels for positron emission tomography.

Review 3. Molecular imaging with PET.

4. Fast and high-yield microreactor syntheses of ortho-substituted [(18)F]fluoroarenes from reactions of [(18)F]fluoride ion with diaryliodonium salts.

5. Positron emission tomography provides molecular imaging of biological processes.

6. Palladium-catalyzed asymmetric synthesis of allylic fluorides.

7. Mechanism of C-F reductive elimination from palladium(IV) fluorides.

8. Carbon-fluorine reductive elimination from a high-valent palladium fluoride.

9. Formation of ArF from LPdAr(F): catalytic conversion of aryl triflates to aryl fluorides.

Review 10. Understanding organofluorine chemistry. An introduction to the C-F bond.

1. Direct arene C-H fluorination with ¹⁸F^- via organic photoredox catalysis.

2. Oxidative aliphatic C-H fluorination with manganese catalysts and fluoride ion.

3. Copper-Mediated Fluorination of Aryl Trisiloxanes with Nucleophilic Fluoride.

Review 4. Hypervalent Iodine Reagents in High Valent Transition Metal Chemistry.

5. An automated synthesizer for electrochemical ¹⁸F-fluorination of organic compounds.

6. Synthesis and imaging validation of [¹⁸F]MDL100907 enabled by Ni-mediated fluorination.

7. Copper-Mediated Aminoquinoline-Directed Radiofluorination of Aromatic C-H Bonds with K¹⁸ F.

8. Copper-mediated fluorination of arylboronate esters. Identification of a copper(III) fluoride complex.

9. An azeotropic drying-free approach for copper-mediated radiofluorination without addition of base.

10. (Poly)cationic λ³-Iodane Mediated Oxidative Ring Expansion of Secondary Alcohols.