Literature DB >> 2305931

Chromophobe cell carcinoma: analysis of five cases.

S M Bonsib1, D J Lager.   

Abstract

Five cases of a recently characterized renal neoplasm, chromophobe cell carcinoma, encountered during an ultrastructural and DNA flow cytometric study of renal cortical neoplasms are described. These tumors usually are dark on gross examination and often are associated with focal hemorrhage or necrosis. Microscopically the tumor cell cytoplasm ranges from clear to eosinophilic, potentially eliciting a broad differential diagnosis encompassing renal cell carcinoma and oncocytoma. Ultrastructural studies disclosed the diagnostically required numerous complex cytoplasmic vesicles of unknown composition and origin, and DNA ploidy studies revealed an aneuploid cell population in three of five cases, which correlates with the malignant potential.

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Year:  1990        PMID： 2305931     DOI： 10.1097/00000478-199003000-00007

Source DB:  PubMed          Journal:  Am J Surg Pathol        ISSN： 0147-5185            Impact factor:   6.394


  8 in total

1.  Multiple Synchronous Tumors in a Patient: A Rare Entity.

Authors:  Panteleimon Tsipas; Georgios Laoutides; Athanassios Archontakis; Dimitrios Sampaziotis; Christophoros Kotoulas
Journal:  J Gastrointest Cancer       Date:  2012-09

Review 2.  Renal oncocytoma, yet another tumour that does not fit in the dualistic benign/malignant paradigm?

Authors:  Th Van der Kwast; B Perez-Ordoñez
Journal:  J Clin Pathol       Date:  2007-06       Impact factor: 3.411

3.  Specific loss of chromosomes 1, 2, 6, 10, 13, 17, and 21 in chromophobe renal cell carcinomas revealed by comparative genomic hybridization.

Authors:  M R Speicher; B Schoell; S du Manoir; E Schröck; T Ried; T Cremer; S Störkel; A Kovacs; G Kovacs
Journal:  Am J Pathol       Date:  1994-08       Impact factor: 4.307

4.  Can renal oncocytoma be differentiated from its renal mimics? The utility of anti-mitochondrial, caveolin 1, CD63 and cytokeratin 14 antibodies in the differential diagnosis.

Authors:  Ozgur Mete; Isin Kilicaslan; Mine G Gulluoglu; Veli Uysal
Journal:  Virchows Arch       Date:  2005-08-17       Impact factor: 4.064

5.  Ultrastructural appearance and cytoskeletal architecture of the clear, chromophilic, and chromophobe types of human renal cell carcinoma in vitro.

Authors:  C D Gerharz; R Moll; S Störkel; U Ramp; W Thoenes; H E Gabbert
Journal:  Am J Pathol       Date:  1993-03       Impact factor: 4.307

6.  Chromophobe renal cell carcinoma with microcystic and adenomatous arrangement and pigmentation--a diagnostic pitfall. Morphological, immunohistochemical, ultrastructural and molecular genetic report of 20 cases.

Authors:  O Hes; T Vanecek; D M Perez-Montiel; I Alvarado Cabrero; M Hora; S Suster; J Lamovec; R Curik; V Mandys; M Michal
Journal:  Virchows Arch       Date:  2005-03-09       Impact factor: 4.064

7.  Establishment and characterization of two divergent cell lines derived from a human chromophobe renal cell carcinoma.

Authors:  C D Gerharz; R Moll; S Störkel; U Ramp; B Hildebrandt; G Molsberger; P Koldovsky; H E Gabbert
Journal:  Am J Pathol       Date:  1995-04       Impact factor: 4.307

8.  Cytomorphological, cytogenetic, and molecular biological characterization of four new human renal carcinoma cell lines of the clear cell type.

Authors:  C D Gerharz; U Ramp; J Olert; R Moll; S Störkel; N Marx; H E Gabbert
Journal:  Virchows Arch       Date:  1994       Impact factor: 4.064
  8 in total

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