Literature DB >> 23058030

Surgical debridement plus topical cyclosporine A in the treatment of vernal shield ulcers.

R Caputo1, N Pucci, F Mori, C De Libero, L Di Grande, G M Bacci.   

Abstract

Vernal keratoconjunctivitis (VKC) is a severe chronic bilateral inflammation of the ocular surface characterized by seasonal exacerbations. Long-term prognosis is generally good; however, 6% develop sequelae responsible for permanent visual impairment. Corneal involvement is almost always present, consisting of punctate keratitis, shield ulcers (3-11%) and late corneal neovascularization. In recent years, topical cyclosporine A preparations at 2% in oil or at 1% in polyvinyl alcohol, have been successfully proposed for long term VKC treatments. It has been previously proven that medical treatment is not always sufficient, especially when it is employed to treat shield ulcer plaques. In such conditions, surgery may be effective for avoiding long term complications such as amblyopia, strabismus, infections and corneal perforation. In this paper, we show the efficacy of surgical debridement by means of simple scraping associated with topical cyclosporine treatment for the management of vernal shield ulcers complicated with plaques.

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Year:  2012        PMID: 23058030     DOI: 10.1177/039463201202500326

Source DB:  PubMed          Journal:  Int J Immunopathol Pharmacol        ISSN: 0394-6320            Impact factor:   3.219


  2 in total

1.  Vernal shield ulcers treated with frequently installed topical cyclosporine 0.05% eyedrops.

Authors:  Tim Westland; Eliza K Patryn; Carla P Nieuwendaal; Ivanka J E van der Meulen; Maarten P Mourits; Ruth Lapid-Gortzak
Journal:  Int Ophthalmol       Date:  2017-01-24       Impact factor: 2.031

2.  Surgical debridement of corneal shield ulcers in pediatric patients: two case reports and a review of the literature.

Authors:  Ricardo Alexandre Stock; Silvia Letícia Teixeira Lazzari; Isadora Proner Martins; Elcio Luiz Bonamigo
Journal:  J Med Case Rep       Date:  2020-06-17
  2 in total

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